Glumetinib Impurity 13 CAS CATO-C4X-325913

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-325913
Molecular FormulaC21H17N9O2S
Molecular Weight459.48 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Glumetinib Impurity 13 CAS CATO-C4X-325913 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 459.48 g/mol gives Glumetinib Impurity 13 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Glumetinib Impurity 13 (CAS CATO-C4X-325913) is a certified pharmaceutical impurity reference standard with the molecular formula C21H17N9O2S and a molecular weight of 459.48 g/mol.

The molecular framework of Glumetinib Impurity 13 (C21H17N9O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Glumetinib Impurity 13 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC21H17N9O2S
Molecular Weight459.48 g/mol
Purity≥95%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)18.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms9
Sulfur Atoms1

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