Lurbinectedin Impurity 16 CAS 497871-81-5
| CAS No. | 497871-81-5 |
| Molecular Formula | C42H46N4O9S |
| Molecular Weight | 782.90 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Lurbinectedin Impurity 16 (CAS 497871-81-5), a pharmacopoeial impurity reference standard (molecular formula C42H46N4O9S, MW 782.90 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Lurbinectedin Impurity 16 (C42H46N4O9S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 22.0, corresponding to approximately 22 ring(s) or double-bond equivalent(s). With a molecular weight of 782.90 g/mol, it falls into the high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C42H46N4O9S |
| Molecular Weight | 782.90 g/mol |
| Purity | 95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 22.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Lurbinectedin Standards
- Lurbinectedin Impurity 10 (CAS CATO-C4X-311410)
- Lurbinectedin Impurity 15 (CAS 2248127-59-3)
- Lurbinectedin Impurity 17 (CAS 2248127-63-9)
- Lurbinectedin (CAS 497871-47-3)
- Lurbinectedin Impurity 27 (CAS 2749898-64-2)
- Lurbinectedin Impurity 35 (CAS CATO-C4X-311435)
- Lurbinectedin Impurity 37 (CAS CATO-C4X-311437)
- Lurbinectedin Impurity 11 (CAS CATO-C4X-311411)
Recommended Standards
- 4,4',4'',4'''-(21H,23H-Porphine-5,10,15,20-tetrayl)tetrakis[benzenecarboximidamide] (CAS 1021170-41-1)
- 362472-82-0 25Q6Y8Y108 Withanoside VI UNII-25Q6Y8Y108 Ergosta-5,24-dien-26-oic acid, 3-((6-o-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy)-1,20,22-trihydroxy-, sigma-lactone, (1alpha,3beta,22R)- Withanoside VI (constituent of ashwagandha root) [DSC] Withanoside vi, (-)- (CAS 362472-82-0)
- PAR-1 (1-6) (mouse, rat) (CAS 140436-67-5)
- Withanoside IV (CAS 362472-81-9)
- Temozolomide Impurity 10 (CAS 90801-87-9)
- Bendamustine impurity 32 (CAS CATO-C4X-127132)
- Posaconazole Impurity 40 (CAS 1370190-94-5)
- (1R,3S)-3-(2-(2-nitrophenyl)-2-oxoethyl)cyclopentane-1-carboxylic acid (CAS 733740-48-2)
- 4-chloro-3-(piperidin-1-ylsulfonyl)aniline (CAS 560995-29-1)
- 1,2,4-Benzenetricarboxylic Acid 1-(2-ethylhexyl) Ester (CAS 61137-09-5)
- 2,6-Diisopropoxyanthracene-9,10-dione (CAS 91854-17-0)
- Vitamin K1 Impurity 32 (CAS 4444-13-7)
- 4-(Phenoxymethyl)piperidine (CAS 63614-86-8)
- Semaglutide impurity 274 (CAS CATO-C4X-2226274)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com