4-{4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}pyrimidin-2-amine CAS 499796-52-0
| CAS No. | 499796-52-0 |
| Molecular Formula | C15H11F3N4S |
| Molecular Weight | 336.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-{4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}pyrimidin-2-amine (CAS 499796-52-0), a certified reference material (molecular formula C15H11F3N4S, MW 336.33 g/mol) for analytical method development and quality control.
4-{4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}pyrimidin-2-amine (C15H11F3N4S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H11F3N4S |
| Molecular Weight | 336.33 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related methyl Standards
- (2E)-2-({[3-(trifluoromethyl)phenyl]amino}methylidene)-3,4-dihydro-2H-1,4-benzothiazin-3-one (CAS 478042-63-6)
- [1-(trifluoromethyl)-2-oxabicyclo[2.1.1]hexan-4-yl]methyl 4-methylbenzenesulfonate (CAS 2770347-99-2)
- 1-((2-(Trifluoromethyl)phenyl)sulfonyl)piperidine-4-carboxamide (CAS 878909-79-6)
- 2-Phenyl-5-({[4-(trifluoromethyl)phenyl]methyl}sulfanyl)-1,3,4-oxadiazole (CAS 477846-61-0)
- 4-(2-(Trifluoromethyl)benzyl)tetrahydro-2h-thiopyran-4-carboxylic acid 1,1-dioxide (CAS 2197052-41-6)
- 4-(3-(Trifluoromethyl)benzyl)tetrahydro-2h-thiopyran-4-carboxylic acid 1,1-dioxide (CAS 2197062-13-6)
- 4-(4-(Trifluoromethyl)benzyl)tetrahydro-2h-thiopyran-4-carboxylic acid 1,1-dioxide (CAS 2197056-70-3)
- 4-{4-Methyl-2-[3-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}pyrimidin-2-amine (CAS 499795-87-8)
Recommended Standards
- 5-[2-(Methylsulfanyl)phenyl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole (CAS 339015-63-3)
- 4-(Benzyloxy)cyclohex-1-en-1-yl trifluoromethanesulfonate (CAS 317831-30-4)
- 5-[2-(Methylsulfanyl)phenyl]-3-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazole (CAS 339099-65-9)
- 6-((3-(Trifluoromethyl)phenyl)thio)quinazoline-2,4-diamine (CAS 51123-99-0)
- 2-(3-Phenylpropanamido)benzoic acid (CAS 142005-11-6)
- 1-(M-tolyl)pentan-1-one (CAS 20359-57-3)
- 5-((Benzyloxy)methyl)pyrimidine-2,4(1H,3H)-dione (CAS 7295-02-5)
- trans-1-(Boc-amino)-4-cyanocyclohexane (CAS 873537-32-7)
- (3S,5S)-3,5-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-hydroxy-cyclohexanecarboxylic Acid Methyl Ester (CAS 139356-33-5)
- 2-Chloro-4-(p-tolyl)nicotinonitrile (CAS 886362-03-4)
- 3-Methyl-2-nitro-1H-indole (CAS 19869-26-2)
- 9Alpha-11alpha,15s-trihydroxy-prosta-5z,13e-dien-1-oic-3,3,4,4-d4acid (CAS 34210-11-2)
- Insulin B (22-25) (CAS 34367-73-2)
- Des-His(1)-Semaglutide (CAS CATO-C4X-2226216)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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