5-Bromo-4-{4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}pyrimidin-2-amine CAS 499796-53-1
| CAS No. | 499796-53-1 |
| Molecular Formula | C15H10BrF3N4S |
| Molecular Weight | 415.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Bromo-4-{4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}pyrimidin-2-amine.
CATO supplies 5-Bromo-4-{4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}pyrimidin-2-amine (CAS 499796-53-1), a certified reference material (molecular formula C15H10BrF3N4S, MW 415.23 g/mol) for analytical method development and quality control.
Based on its molecular formula C15H10BrF3N4S, 5-Bromo-4-{4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}pyrimidin-2-amine contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 415.23 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Bromo-4-{4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}pyrimidin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H10BrF3N4S |
| Molecular Weight | 415.23 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 2-(5-Bromo-2-fluorophenyl)-2-methyl-1-((2-nitrophenyl)sulfonyl)aziridine (CAS 1386986-56-6)
- 5-Bromo-4-{4-methyl-2-[3-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}pyrimidin-2-amine (CAS 499795-95-8)
- (S)-2-(2-(5-Bromo-1H-indol-3-yl)-2-oxoacetamido)-3-phenylpropanoic acid (CAS 94751-07-2)
- 2-(2-(5-Bromo-1H-indol-3-yl)-2-oxoacetamido)-3-phenylpropanoic acid (CAS 97500-76-0)
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Recommended Standards
- 2-(4-bromophenyl)-2-oxoethyl 6-cyclopropyl-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylate (CAS 1795506-99-8)
- 2,2-Difluoro-N-(4-(trifluoromethoxy)phenyl)-2-(3-(trifluoromethyl)phenoxy)acetamide (CAS 338792-04-4)
- (3-Amino-6-methyl-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl)(4-bromophenyl)methanone (CAS 299198-16-6)
- 3-(5-(4-Bromophenyl)furan-2-yl)-N-(2-nitrophenyl)propanamide (CAS 853331-06-3)
- 1,2-Bis(bromomethyl)-3-methoxybenzene (CAS 71785-96-1)
- Ethyl 4,7-dimethyl-1H-indole-2-carboxylate (CAS 59549-48-3)
- 2-methyl-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)propan-2-ol (CAS 1415793-95-1)
- 1-Bromo-2-((3-fluorophenoxy)methyl)benzene (CAS 877663-37-1)
- Pyrazolo[1,5-a]pyrimidine-5-carbaldehyde (CAS 1780675-33-3)
- 3-bromo-1-benzofuran-2-sulfonyl chloride (CAS 128852-14-2)
- (3aR,3′aR,8aS,8′aS)-2,2′-[2-(4-Tricyclo[3.3.1.13,7]dec-1-ylphenyl)-1-[(4-tricyclo[3.3.1.13,7]dec-1-ylphenyl)methyl]ethylidene]bis[3a,8a-dihydro-8H-indeno[1,2-d]oxazole] (CAS 2757085-49-5)
- 3-(((1R,2R)-2-Fluorocyclopropyl)sulfonyl)benzonitrile (CAS 2375924-16-4)
- 2-Bromo-4-chloro-5-fluoroaniline (CAS 120694-11-3)
- Biotinyl-Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 1816258-36-2)
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