N-Nitroso Lomustine Impurity 2 CAS 500545-48-2

Description

Compared with other compounds in its class, the molecular weight of 315.84 g/mol gives N-Nitroso Lomustine Impurity 2 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies N-Nitroso Lomustine Impurity 2 (CAS 500545-48-2), a pharmacopoeial impurity reference standard (molecular formula C15H26ClN3O2, MW 315.84 g/mol) used for the identification and quantification of trace impurities in APIs.

N-Nitroso Lomustine Impurity 2 (C15H26ClN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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