Metaraminol Impurity 60 CAS 501-53-1
| CAS No. | 501-53-1 |
| Molecular Formula | C8H7ClO2 |
| Molecular Weight | 170.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Metaraminol Impurity 60 (CAS 501-53-1) is a certified pharmaceutical impurity reference standard with the molecular formula C8H7ClO2 and a molecular weight of 170.59 g/mol.
Based on its molecular formula C8H7ClO2, Metaraminol Impurity 60 contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 170.59 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C8H7ClO2 |
| Molecular Weight | 170.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Metaraminol Standards
- Metaraminol Impurity 52 (CAS CATO-C4X-225252)
- Metaraminol Impurity 27 (CAS 21480-43-3)
- Metaraminol Impurity 30 (CAS 54-49-9)
- Metaraminol Impurity 41 (CAS 61-59-6)
- Metaraminol Impurity 56 (CAS CATO-C4X-225256)
- Metaraminol Impurity 8 (CAS 21480-44-4)
- Metaraminol Impurity 27 (CAS 78523-29-2)
- Metaraminol Impurity 10 (CAS 639070-81-8)
Recommended Standards
- Tulobuterol Impurity 3 (CAS 133662-20-1)
- 4-Chloro-2-Methylbenzoic Acid (CAS 7499-07-2)
- Epinephrine Impurity 13 (CAS 6305-04-0)
- Methyl 2-Chlorobenzoate (CAS 610-96-8)
- Benzbromarone Impurity 15 (CAS 79302-23-1)
- Mirabegron Impurity 12 (CAS CATO-C4X-103212)
- Upadacitinib Impurity 163 (CAS CATO-C4X-2405163)
- 3-Amino-N-cyclohexyl-2-hydroxy-N-methylbenzamide (CAS 473731-12-3)
- 2-Formyl-3-hydroxy-N,N-dimethylbenzamide (CAS 1243344-35-5)
- Benzyl (S)-2-(aminomethyl)morpholine-4-carboxylate (CAS 1881275-91-7)
- 49625-94-7 Sodium 3-(benzothiazol-2-ylthio)propanesulphonate 1-Propanesulfonic acid, 3-(2-benzothiazolylthio)-, sodium salt (1:1) 1-Propanesulfonic acid, 3-(2-benzothiazolylthio)-, sodium salt EINECS 256-401-8 (CAS 49625-94-7)
- Ticagrelor Impurity 152 (CAS 1006376-62-0)
- Methyl 3-[(4-methylphenyl)sulfanyl]-4-nitrobenzoate (CAS 1280787-23-6)
- Tirzepatide Impurity 38 (CAS CATO-C4X-324038)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com