Ticagrelor Impurity 152 CAS 1006376-62-0
| CAS No. | 1006376-62-0 |
| Molecular Formula | C10H9F2NO |
| Molecular Weight | 197.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ticagrelor Impurity 152.
Ticagrelor Impurity 152 (CAS 1006376-62-0) is a certified pharmaceutical impurity reference standard with the molecular formula C10H9F2NO and a molecular weight of 197.18 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Ticagrelor Impurity 152 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 197.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ticagrelor Impurity 152 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H9F2NO |
| Molecular Weight | 197.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ticagrelor Standards
- Ticagrelor impurity 136 (CAS 1932275-13-2)
- Ticagrelor impurity 84（trans） (CAS 1006614-51-2)
- Ticagrelor Impurity 74 (CAS 220352-36-3)
- Ticagrelor Impurity 135 (CAS CATO-C4X-1093135)
- Ticagrelor Impurity 173 (CAS 1212376-05-0)
- Ticagrelor Impurity N40 (CAS 1006376-60-8)
- Ticagrelor Impurity 153 (CAS CATO-C4X-1093153)
- Ticagrelor Impurity 78 (CAS 1351990-36-7)
Recommended Standards
- Dichlorocyclohexylmethylsilane (CAS 5578-42-7)
- 1-(3,5-Dimethyl-4-nitro-1h-pyrazol-1-yl)propan-2-one (CAS 1002651-00-4)
- Azetidin-1-yl-(3,4-difluorophenyl)-methanone (CAS 863505-11-7)
- 1-(2-(Dimethylamino)-2-oxoethyl)-1H-pyrazole-4-carboxylic acid (CAS 1006454-68-7)
- Siponimod Impurity 38 (CAS CATO-C4X-247238)
- Polymyxin Impurity 36 TFA (CAS CATO-C4X-225536)
- Etrasimod impurity 15 (CAS CATO-C4X-321415)
- 2-(4-Hydroxyphenyl)-3-propylbenzofuran-5-ol (CAS 76396-32-2)
- Ethyl 2,4-difluoro-3-nitrobenzoate (CAS 1806312-99-1)
- 5-Oxo-1-propylpyrrolidine-3-carbohydrazide (CAS 1437312-25-8)
- Suberic Acid Bis(3-sulfo-N-hydroxysuccinimide ester)-d (CAS 910292-87-4)
- 1036688-17-1 Ethyl 4-fluoro-3-(morpholin-4-ylsulfonyl)benzoate MFCD10816998 (CAS 1036688-17-1)
- 1-(1h-1,3-Benzodiazol-2-yl)-2-methylpropan-2-amine (CAS 39650-66-3)
- Cycloaspeptide D (CAS 691363-62-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com