Metolazone EP Impurity A CAS 50869-25-5
| CAS No. | 50869-25-5 |
| Molecular Formula | C16H16ClN3O3S |
| Molecular Weight | 365.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Metolazone EP Impurity A.
Metolazone EP Impurity A (CAS 50869-25-5), molecular formula C16H16ClN3O3S and molecular weight 365.83 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C16H16ClN3O3S, Metolazone EP Impurity A contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 365.83 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Metolazone EP Impurity A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H16ClN3O3S |
| Molecular Weight | 365.83 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Metolazone Standards
Recommended Standards
- 5-((4-Chlorophenyl)thio)-N-(4-fluorophenyl)-1,2,3-thiadiazole-4-carboxamide (CAS 338791-89-2)
- 4-Chloro-N-(pyridin-2-yl)-3-(pyrrolidin-1-ylsulfonyl)benzamide (CAS 898634-00-9)
- Zidapamide (CAS 75820-08-5)
- 4-Chloro-N-(9-oxo-9H-thioxanthen-2-yl)benzamide (CAS 243472-21-1)
- tert-Butyl tert-butylcarbamate (CAS 71872-03-2)
- (2R,4R)-1-(tert-butoxycarbonyl)-4-hydroxy-2-methylpyrrolidine-2-carboxylic acid (CAS 185026-95-3)
- 3-((2-Chloro-6-fluorobenzyl)thio)-5-propyl-4H-1,2,4-triazol-4-amine (CAS 459210-10-7)
- 7-(4-Bromophenyl)-2-(4-(2-fluorophenyl)piperazin-1-yl)thieno[3,2-d]pyrimidin-4(1H)-one (CAS 1242861-55-7)
- 6-Bromo-N2-ethylpyrazine-2,3-diamine (CAS 117719-10-5)
- (2Z,4E)-Hexa-2,4-dienal (CAS 54716-12-0)
- Brinzolamide Impurity 15 (CAS 165117-54-4)
- 2-{5-[(1E)-1-{[(2,3-dichlorophenyl)methoxy]imino}ethyl]thiophen-2-yl}acetonitrile (CAS 337924-53-5)
- 3-Chloro-N-((tetrahydro-2H-pyran-4-yl)methyl)aniline (CAS 1250728-27-8)
- (Pro30,Tyr32,Leu34)-Neuropeptide Y (28-36) (CAS 161650-01-7)
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