5-Chlorobenzo[c]isothiazol-3-amine CAS 51357-79-0
| CAS No. | 51357-79-0 |
| Molecular Formula | C7H5ClN2S |
| Molecular Weight | 184.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 5-Chlorobenzo[c]isothiazol-3-amine (CAS 51357-79-0), a certified reference material (molecular formula C7H5ClN2S, MW 184.65 g/mol) for analytical method development and quality control.
Owing to a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system, 5-Chlorobenzo[c]isothiazol-3-amine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 184.65 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 5-Chlorobenzo[c]isothiazol-3-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5ClN2S |
| Molecular Weight | 184.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorobenzo Standards
- 7-Chlorobenzo[d]thiazol-5-amine (CAS 196205-26-2)
- 2-Chlorobenzo[d]thiazol-4-amine (CAS 855283-00-0)
- 2-Chlorobenzo[d]thiazol-6-amine (CAS 2406-90-8)
- 4-Chlorobenzo[d]isothiazol-3-amine (CAS 25380-80-7)
- 4-Chlorobenzo[d]isothiazol-7-amine (CAS 35271-94-4)
- 4-Chlorobenzo[d]thiazol-5-amine (CAS 70202-01-6)
- 4-Chlorobenzo[d]thiazol-7-amine (CAS 70202-02-7)
- 5-Chlorobenzo[d]isothiazol-3-amine (CAS 69504-56-9)
Recommended Standards
- 5-Chloro-6-methylbenzo[c][1,2,5]thiadiazole (CAS 50636-02-7)
- 5-Chloro-1H-pyrrolo[2,3-b]pyridine-4-thiol (CAS 2415987-86-7)
- 6-Chloro-2-methylthiazolo[5,4-b]pyridine (CAS 857970-22-0)
- 5-Chloro-1,3-dihydro-2H-benzo[d]imidazole-2-thione (CAS 25369-78-2)
- 2-Bromo-5,5-dimethyl-4,5,6,7-tetrahydrobenzo[b]thiophen-4-amine (CAS 2092048-46-7)
- Terbinafine Hydrochloride (CAS 78628-80-5)
- Rotigotine Impurity 7 (CAS 94425-22-6)
- (2-azidoethyl)dimethylamine hydrochloride (CAS 86311-36-6)
- 1-(3-Chlorophenyl)pyrazole (CAS 57211-65-1)
- tert-Butyl 4-((2-methoxyphenyl)carbamoyl)piperidine-1-carboxylate (CAS 1090389-04-0)
- Erastin (CAS 571203-78-6)
- 4-Iodo-2-isopropyl-1-methyl-1H-imidazole (CAS 851870-24-1)
- 2-Fluoro-6-nitro-4-(trifluoromethyl)aniline (CAS 1217304-18-1)
- Semaglutide Impurity 148 (CAS CATO-C4X-2226148)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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