5-Chloro-1H-pyrrolo[2,3-b]pyridine-4-thiol CAS 2415987-86-7
| CAS No. | 2415987-86-7 |
| Molecular Formula | C7H5ClN2S |
| Molecular Weight | 184.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Chloro-1H-pyrrolo[2,3-b]pyridine-4-thiol is closely related to a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-Chloro-1H-pyrrolo[2,3-b]pyridine-4-thiol (CAS 2415987-86-7), a certified reference material (molecular formula C7H5ClN2S, MW 184.65 g/mol) for analytical method development and quality control.
The molecular framework of 5-Chloro-1H-pyrrolo[2,3-b]pyridine-4-thiol (C7H5ClN2S) is characterized by a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-Chloro-1H-pyrrolo[2,3-b]pyridine-4-thiol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5ClN2S |
| Molecular Weight | 184.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 4-Chloro-6-methylthieno[2,3-d]pyrimidine (CAS 106691-21-8)
- 5-chloro-1,3-benzothiazol-4-amine (CAS 1087784-64-2)
- 5-chloro-2-methyl-thiazolo[5,4-b]pyridine (CAS 109202-21-3)
- 4-Chloro-6-methylthiazolo[4,5-c]pyridine (CAS 1159829-49-8)
- 5-Chloro-2-methylthiazolo[4,5-b]pyridine (CAS 118872-73-4)
- 2-Chloro-5-methylthiazolo[5,4-b]pyridine (CAS 1190927-27-5)
- 6-Chloro-3-methylisothiazolo[5,4-b]pyridine (CAS 129211-90-1)
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Recommended Standards
- 5-Chloro-1,3-dihydro-2H-benzo[d]imidazole-2-thione (CAS 25369-78-2)
- 5-Chloro-6-methylbenzo[c][1,2,5]thiadiazole (CAS 50636-02-7)
- 5-Amino-2-chlorobenzothiazole (CAS 80945-82-0)
- 5-Chlorobenzo[c]isothiazol-3-amine (CAS 51357-79-0)
- N-(2-Bromophenyl)-6-hydroxy-1-methyl-2-oxo-1,2-dihydropyrimidine-4-carboxamide (CAS 338774-78-0)
- 3-Difluoromethylaniline (CAS 368-99-0)
- 1-(4-Chlorophenyl)-1,5-dihydro-4-(4-morpholinyl)-2H-imidazol-2-one (CAS 188116-07-6)
- 4,4’-Di-tert-butylbenzoin (CAS 77387-64-5)
- 4-Hydroxy-1H-imidazo[4,5-c]pyridin-6(5H)-one (CAS 91160-07-5)
- 4-Methyl-1H-pyrrolo[2,3-c]pyridine hydrochloride (CAS 1314354-22-7)
- 5-Butoxy-2,4-difluorophenol (CAS 1881320-56-4)
- 2-chloro-N-cyclopentylpyridin-3-amine (CAS 906371-82-2)
- (4S,5R)-4-(Hydroxymethyl)-2-phenyl-1,3-dioxan-5-ol (CAS 81577-58-4)
- Insulin Degludec Impurity 9 (CAS CATO-C4X-21579)
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