(R)-2-Hydroxy-2-(3-(trifluoromethyl)phenyl)aceticacid CAS 51359-73-0
| CAS No. | 51359-73-0 |
| Molecular Formula | C9H7F3O3 |
| Molecular Weight | 220.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (R)-2-Hydroxy-2-(3-(trifluoromethyl)phenyl)aceticacid.
CATO supplies (R)-2-Hydroxy-2-(3-(trifluoromethyl)phenyl)aceticacid (CAS 51359-73-0), a certified reference material (molecular formula C9H7F3O3, MW 220.15 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, (R)-2-Hydroxy-2-(3-(trifluoromethyl)phenyl)aceticacid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 220.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (R)-2-Hydroxy-2-(3-(trifluoromethyl)phenyl)aceticacid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H7F3O3 |
| Molecular Weight | 220.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | F-containing |
Related R Standards
- Methyl 2-hydroxy-6-(trifluoromethyl)benzoate (CAS 1024605-95-5)
- Methyl 2-hydroxy-2-(2,4,5-trifluorophenyl)acetate (CAS 1036273-10-5)
- 2-(4-Hydroxy-3-(trifluoromethyl)phenyl)acetic acid (CAS 1042703-41-2)
- 2-Hydroxy-4’-(trifluoromethoxy)acetophenone (CAS 1148005-60-0)
- Methyl 4-hydroxy-3-(trifluoromethyl)benzoate (CAS 115933-50-1)
- 2-Hydroxy-4-methyl-6-(trifluoromethyl)nicotinamide (CAS 116548-07-3)
- (2s)-2-Hydroxy-2-[3-(trifluoromethyl)phenyl]acetic acid (CAS 1198319-99-1)
- Methyl 2-hydroxy-5-(trifluoromethyl)benzoate (CAS 1261478-26-5)
Recommended Standards
- (R)-1-(Benzo[d][1,3]dioxol-5-yl)-2,2,2-trifluoroethan-1-ol (CAS 945732-89-8)
- (S)-3,3,3-trifluoro-2-hydroxy-2-phenylpropanoic acid (CAS 29246-94-4)
- (3-Nitro-5-(trifluoromethyl)phenyl)methanamine (CAS 771582-29-7)
- {[5-(Trifluoromethyl)pyridin-2-yl]amino}acetic acid (CAS 923216-18-6)
- 3-(2-(4-Methylpiperazin-1-yl)ethoxy)aniline (CAS 890652-00-3)
- 4-(4-ethoxyphenoxy)aniline hydrochloride (CAS 6889-04-9)
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- methyl 6-chloropyridazine-3-carboxylate (CAS 65202-50-8)
- 3,5-Diiodo-4-methoxy-1-methylpyridin-2(1H)-one (CAS 920490-66-0)
- 4-(((1,3-Dimethyl-1H-pyrazol-4-yl)methyl)amino)butan-1-ol hydrochloride (CAS 1856076-07-7)
- 2-(2-Methylpropoxy)-5-(trifluoromethyl)pyridin-3-ol (CAS 1881321-32-9)
- (1Z,3Z)-1,3-Bis[[(4S)-4,5-dihydro-4-phenyl-2-oxazolyl]methylene]-2,3-dihydro-5,6-dimethyl-1H-isoindole (CAS 1358991-79-3)
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