(R)-Flurbiprofen CAS 51543-40-9
| CAS No. | 51543-40-9 |
| Molecular Formula | C15H13FO2 |
| Molecular Weight | 244.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (R)-Flurbiprofen.
(R)-Flurbiprofen (CAS 51543-40-9), molecular formula C15H13FO2 and molecular weight 244.26 g/mol, is a CATO reference standard with documented purity and traceability.
(R)-Flurbiprofen (C15H13FO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H13FO2 |
| Molecular Weight | 244.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | F-containing |
Related R Standards
- Flurbiprofen impurity 119 (CAS CATO-C4X-1444119)
- Flurbiprofen Impurity 160 (CAS 607361-34-2)
- Flurbiprofen Impurity 161 (CAS CATO-C4X-1444161)
- (S)-Flurbiprofen (CAS 51543-39-6)
- Flurbiprofen Impurity 80 (CAS CATO-C4X-144480)
- Flurbiprofen (CAS 5104-49-4)
- Flurbiprofen impurity 120 (CAS 87657-78-1)
- Flurbiprofen Impurity 158 (CAS CATO-C4X-1444158)
Recommended Standards
- Tiapride EP Impurity A (CAS 63484-12-8)
- Tamsulosin Impurity 41 (CAS CATO-C4X-118741)
- (R)-2-(Tosyloxy)propanoic Acid (CAS 130368-69-3)
- Penicillenic Acid (CAS 10250-99-4)
- 5-(1-Tosylpiperidin-2-yl)pyridin-2-amine (CAS 1352482-54-2)
- 3-Ethylsalicylaldehyde (CAS 73289-91-5)
- 5-[[(2R)-2-amino-3-hydroxy-propyl]amino]-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione (CAS 2728861-00-3)
- Ethyl 4-amino-1-(methoxymethyl)-1H-imidazole-2-carboxylate (CAS 1026411-22-2)
- 6-Cyano-2-(trifluoromethyl)nicotinic acid (CAS 1211537-27-7)
- N-(2-(2-carbamothioylhydrazinyl)-2-oxoethyl)benzamide (CAS 83530-35-2)
- Ethyl 7-bromo-5-nitrobenzofuran-2-carboxylate (CAS 1010072-35-1)
- 3-Methylbenzofuran-2-carboxylic Acid (CAS 24673-56-1)
- 2-{[(4-methoxyphenyl)sulfonyl]amino}-4-methylpentanoic acid (CAS 202751-32-4)
- Glucagon (19-29) (human, rat, porcine) (CAS 64790-15-4)
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