Fmoc-(R)-3-amino-3-(3-trifluoromethylphenyl)-propionic acid CAS 517905-87-2
| CAS No. | 517905-87-2 |
| Molecular Formula | C25H20F3NO4 |
| Molecular Weight | 455.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Fmoc-(R)-3-amino-3-(3-trifluoromethylphenyl)-propionic acid is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Fmoc-(R)-3-amino-3-(3-trifluoromethylphenyl)-propionic acid (CAS 517905-87-2), a certified reference material (molecular formula C25H20F3NO4, MW 455.43 g/mol) for analytical method development and quality control.
Fmoc-(R)-3-amino-3-(3-trifluoromethylphenyl)-propionic acid (C25H20F3NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H20F3NO4 |
| Molecular Weight | 455.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fmoc Standards
- Fmoc-(RS)-3-amino-3-(3-trifluoromethylphenyl)-propionic acid (CAS 181953-60-6)
- Fmoc-(R)-3-Amino-3-(4-trifluoromethylphenyl)-propionic acid (CAS 517905-88-3)
- Fmoc-(RS)-3-amino-3-(4-trifluoromethylphenyl)-propionic acid (CAS 728919-94-6)
- Fmoc-(S)-3-amino-3-(2-trifluoromethylphenyl)-propionic acid (CAS 507472-19-7)
- Fmoc-(S)-3-Amino-3-(3-trifluoromethyl-phenyl)-propionic acid (CAS 507472-20-0)
- Fmoc-(S)-3-Amino-3-(4-trifluoromethylphenyl)-propionic acid (CAS 507472-21-1)
- Fmoc-2-(trifluoromethyl)-L-phenylalanine (CAS 352523-16-1)
- Fmoc-D-Phe(4-CF3)-OH (CAS 238742-88-6)
Recommended Standards
- 3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-(trifluoromethyl)phenyl)propanoic acid (CAS 954225-58-2)
- (S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic acid (CAS 959580-94-0)
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-(trifluoromethyl)phenyl)propanoic acid (CAS 205526-27-8)
- (R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-(trifluoromethyl)phenyl)propanoic acid (CAS 517905-86-1)
- 2-Amino-3-methyl-N-(1-(o-tolyl)ethyl)butanamide (CAS 1290851-02-3)
- N-Cyclohexyl-4-(piperazin-1-yl)benzamide hydrochloride (CAS 2176124-88-0)
- 5-Ethynyl-2-fluoropyridine (CAS 853909-08-7)
- 6-Chloro-5-methoxy-3-methyl-1H-indole-2-carbaldehyde (CAS 1368473-04-4)
- 2-Chloro-N-methylethanamine hydrochloride (CAS 4535-90-4)
- Clopidogrel Impurity 30 (CAS 69061-17-2)
- 2-Ethyl-6-(1H-pyrrol-1-yl)-1,3-benzoxazole (CAS 861206-65-7)
- 5-Amino-1-benzyl-3-methylpyridin-2(1H)-one (CAS 2271477-28-0)
- Methyl 2-chloro-5-formylnicotinate (CAS 176433-61-7)
- [α-Glu](Side Chain)-Semaglutide (CAS CATO-C4X-2226159)
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