3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-(trifluoromethyl)phenyl)propanoic acid CAS 954225-58-2
| CAS No. | 954225-58-2 |
| Molecular Formula | C25H20F3NO4 |
| Molecular Weight | 455.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-(trifluoromethyl)phenyl)propanoic acid (CAS 954225-58-2) is a high-purity analytical reference standard with the molecular formula C25H20F3NO4 and a molecular weight of 455.43 g/mol.
3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-(trifluoromethyl)phenyl)propanoic acid (C25H20F3NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H20F3NO4 |
| Molecular Weight | 455.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related H Standards
- 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-methyl-4-phenylthiophene-3-carboxylic acid (CAS 1217863-68-7)
- 2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-8-thia-2-azaspiro[4.5]decane-4-carboxylic acid 8,8-dioxide (CAS 1823835-45-5)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-bromo-5-fluorobenzoic acid (CAS 2243510-53-2)
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- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-bromo-5-fluorobenzoic acid (CAS 2243507-07-3)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-bromo-3-fluorobenzoic acid (CAS 2243513-70-2)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,4-dichlorophenyl)propanoic acid (CAS 1105045-80-4)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-2-(2,3-dichlorophenyl)acetic acid (CAS 1692781-66-0)
Recommended Standards
- (S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic acid (CAS 959580-94-0)
- Fmoc-(R)-3-amino-3-(3-trifluoromethylphenyl)-propionic acid (CAS 517905-87-2)
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-(trifluoromethyl)phenyl)propanoic acid (CAS 205526-27-8)
- Fmoc-(R)-3-Amino-3-(4-trifluoromethylphenyl)-propionic acid (CAS 517905-88-3)
- 2-(5-Amino-1h-indol-1-yl)acetamide (CAS 1094458-54-4)
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