Medroxyprogesterone CAS 520-85-4
| CAS No. | 520-85-4 |
| Molecular Formula | C22H32O3 |
| Molecular Weight | 344.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Medroxyprogesterone is closely related to a steroid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Medroxyprogesterone (CAS 520-85-4) is a high-purity analytical reference standard with the molecular formula C22H32O3 and a molecular weight of 344.49 g/mol.
Medroxyprogesterone (C22H32O3) contains a steroid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H32O3 |
| Molecular Weight | 344.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Medroxyprogesterone Standards
- Medroxyprogesterone Impurity N3 (CAS 13254-82-5)
- Medroxyprogesterone Acetate EP Impurity I (CAS CATO-C4X-14573)
- Medroxyprogesterone impurity 10 (CAS 15399-87-8)
- Medroxyprogesterone impurity 9 (CAS 14510-23-7)
- Medroxyprogesterone Acetate Impurity 6 (CAS 1097-51-4)
- Medroxyprogesterone Acetate EP Impurity H (CAS 302-23-8)
- Medroxyprogesterone Impurity N2 (CAS 77881-13-1)
- Medroxyprogesterone Impurity 13 (CAS CATO-C4X-145713)
Recommended Standards
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