Medroxyprogesterone Impurity N2 CAS 77881-13-1
| CAS No. | 77881-13-1 |
| Molecular Formula | C20H27NO2 |
| Molecular Weight | 313.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Medroxyprogesterone Impurity N2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Medroxyprogesterone Impurity N2 (CAS 77881-13-1), a pharmacopoeial impurity reference standard (molecular formula C20H27NO2, MW 313.43 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C20H27NO2, Medroxyprogesterone Impurity N2 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 313.43 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C20H27NO2 |
| Molecular Weight | 313.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Nitrogen Atoms | 1 |
Related Medroxyprogesterone Standards
- Medroxyprogesterone Acetate Impurity 6 (CAS 1097-51-4)
- Medroxyprogesterone impurity 9 (CAS 14510-23-7)
- Medroxyprogesterone impurity 10 (CAS 15399-87-8)
- Medroxyprogesterone Impurity N3 (CAS 13254-82-5)
- Medroxyprogesterone Acetate EP Impurity I (CAS CATO-C4X-14573)
- Medroxyprogesterone (CAS 520-85-4)
- Medroxyprogesterone Acetate EP Impurity H (CAS 302-23-8)
- Medroxyprogesterone Impurity 13 (CAS CATO-C4X-145713)
Recommended Standards
- 2-(Adamantan-1-yl)-N-(4-ethoxyphenyl)acetamide (CAS 296276-37-4)
- Methyl (S,E)-5-((tert-butoxycarbonyl)amino)-2,2,7-trimethyloct-3-enoate (CAS 2598983-48-1)
- 1-(Adamantan-1-yl)-N-(benzo[d][1,3]dioxol-5-ylmethyl)ethan-1-amine (CAS 312519-09-8)
- tert-butyl 1-[2-hydroxy-3-(propan-2-yloxy)propyl]-7-azabicyclo[2.2.1]heptane-7-carboxylate (CAS 2138979-94-7)
- Methenamine Impurity 4 (CAS 16352-36-6)
- Bicalutamide Impurity 32 (CAS CATO-C4X-101332)
- Azithromycin Impurity 33 (CAS CATO-C4X-100333)
- {spiro[2.5]octan-6-yl}methanol (CAS 849671-56-3)
- 2,4-Dichloro-3-cyano-5-fluorobenzoyl chloride (CAS 117528-59-3)
- 4-Amino-6-bromoisothiochroman 2,2-dioxide hydrochloride (CAS 1211011-78-7)
- 4-Amino-N,N-dimethylbutanamide (CAS 87639-91-6)
- n,n-Diethyl-10h-phenothiazine-10-carboxamide (CAS 20828-88-0)
- 3-(3,4-Dihydroquinolin-1(2H)-ylcarbonyl)-2,2-dimethylcyclopropanecarboxylic acid (CAS 1496936-09-4)
- Semaglutide impurity 95 (CAS CATO-C4X-222695)
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