1-Oxo-1-((3-(trifluoromethyl)phenyl)amino)propan-2-yl 2-(methylthio)nicotinate CAS 522641-19-6
| CAS No. | 522641-19-6 |
| Molecular Formula | C17H15F3N2O3S |
| Molecular Weight | 384.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Oxo-1-((3-(trifluoromethyl)phenyl)amino)propan-2-yl 2-(methylthio)nicotinate (CAS 522641-19-6) is a high-purity analytical reference standard with the molecular formula C17H15F3N2O3S and a molecular weight of 384.37 g/mol.
The molecular framework of 1-Oxo-1-((3-(trifluoromethyl)phenyl)amino)propan-2-yl 2-(methylthio)nicotinate (C17H15F3N2O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-Oxo-1-((3-(trifluoromethyl)phenyl)amino)propan-2-yl 2-(methylthio)nicotinate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H15F3N2O3S |
| Molecular Weight | 384.37 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Oxo Standards
- 2-(4-(2-(Trifluoromethyl)benzoyl)piperazin-1-yl)thiazole-5-carboxamide (CAS 916888-66-9)
- 4-Phenyl-5-{[3-(trifluoromethyl)phenyl]methanesulfonyl}-1,2,3-thiadiazole (CAS 338398-50-8)
- 1-[2-Methyl-6-(trifluoromethyl)pyrimidin-4-yl]-N-[(thiophen-2-yl)methyl]piperidine-4-carboxamide (CAS 1775322-69-4)
- 1-[2-Methyl-6-(trifluoromethyl)pyrimidin-4-yl]-N-(4-methylcyclohexyl)piperidine-4-carboxamide (CAS 1775385-49-3)
- 2-((4-Methyl-5-(trifluoromethyl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 329929-28-4)
- (E)-2-(trifluoromethyl)-3-(2-(4-(trifluoromethyl)benzylidene)hydrazinyl)quinoxaline (CAS 338962-25-7)
- 2-(3,5-Bis(trifluoromethyl)phenyl)quinoline-8-carboxamide (CAS 655222-65-4)
- (2-(Trifluoromethyl)-5-(2-((triisopropylsilyl)oxy)ethyl)thiazol-4-yl)methanol (CAS 1858271-73-4)
Recommended Standards
- 1H-Benzimidazolium, 1,2-dimethyl-3-[(4-sulfophenyl)methyl]-5-(trifluoromethyl)-, inner salt (CAS 68959-22-8)
- 4-(Methylthio)-N-(4-nitrobenzylidene)-2-(4-nitrophenyl)oxazol-5-amine (CAS 31666-15-6)
- 4,6-Dioxo-2-phenyl-1H-pyrazolo[3,4-d]pyrimidin-5(2H,4H,6H)-yl benzenesulfonate (CAS 16078-65-2)
- N-(2-(1H-indol-3-yl)ethyl)-4-(trifluoromethoxy)benzenesulfonamide (CAS 880139-21-9)
- 1-(2-Ethoxypyrrolidin-1-yl)-4-methylpent-3-en-1-one (CAS 259213-88-2)
- 3-Oxospiro[3.3]Heptane-1-carboxylic acid (CAS 2306277-97-2)
- 4-Chloro-3,4-(ethylenedioxy)benzophenone (CAS 101018-98-8)
- N-{[1-(propan-2-yl)cyclopropyl]methylidene}propane-1-sulfinamide (CAS 2164010-87-9)
- Methyl 5-(2-Benzofuryl)isoxazole-3-carboxylate (CAS 1105191-59-0)
- Spiro[chroman-2,4'-piperidine] (CAS 147372-85-8)
- 1-((2,5-Dimethylthiophen-3-yl)sulfonyl)piperidine-3-carboxylic acid (CAS 923744-29-0)
- 2-Methoxyethyl 2-benzylidene-7-methyl-3-oxo-5-(thiophen-2-yl)-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate (CAS 617698-63-2)
- 5-Acetyl-5-hydroxy-3,4-dimethylfuran-2(5H)-one (CAS 335157-95-4)
- Semaglutide impurity 44 (CAS CATO-C4X-222644)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com