2-(4-(2-(Trifluoromethyl)benzoyl)piperazin-1-yl)thiazole-5-carboxamide CAS 916888-66-9
| CAS No. | 916888-66-9 |
| Molecular Formula | C16H15F3N4O2S |
| Molecular Weight | 384.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(4-(2-(Trifluoromethyl)benzoyl)piperazin-1-yl)thiazole-5-carboxamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(4-(2-(Trifluoromethyl)benzoyl)piperazin-1-yl)thiazole-5-carboxamide (CAS 916888-66-9), molecular formula C16H15F3N4O2S and molecular weight 384.38 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-(4-(2-(Trifluoromethyl)benzoyl)piperazin-1-yl)thiazole-5-carboxamide (C16H15F3N4O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 384.38 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H15F3N4O2S |
| Molecular Weight | 384.38 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Trifluoromethyl Standards
- 1-Oxo-1-((3-(trifluoromethyl)phenyl)amino)propan-2-yl 2-(methylthio)nicotinate (CAS 522641-19-6)
- 4-Phenyl-5-{[3-(trifluoromethyl)phenyl]methanesulfonyl}-1,2,3-thiadiazole (CAS 338398-50-8)
- 1-[2-Methyl-6-(trifluoromethyl)pyrimidin-4-yl]-N-[(thiophen-2-yl)methyl]piperidine-4-carboxamide (CAS 1775322-69-4)
- 1-[2-Methyl-6-(trifluoromethyl)pyrimidin-4-yl]-N-(4-methylcyclohexyl)piperidine-4-carboxamide (CAS 1775385-49-3)
- 2-((4-Methyl-5-(trifluoromethyl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 329929-28-4)
- (E)-2-(trifluoromethyl)-3-(2-(4-(trifluoromethyl)benzylidene)hydrazinyl)quinoxaline (CAS 338962-25-7)
- 2-(3,5-Bis(trifluoromethyl)phenyl)quinoline-8-carboxamide (CAS 655222-65-4)
- (2-(Trifluoromethyl)-5-(2-((triisopropylsilyl)oxy)ethyl)thiazol-4-yl)methanol (CAS 1858271-73-4)
Recommended Standards
- 2-((3-(3,4-Dimethoxyphenyl)-2-methyl-4-oxo-4H-chromen-7-yl)oxy)acetohydrazide (CAS 844859-04-7)
- 2-[2-(3,4-Diacetoxy-phenyl)-vinyl]-6-methoxy-benzoic acid methyl ester (CAS 365543-25-5)
- ((1R,2S,5R,6S)-5-(Benzoyloxy)-1,2,6-trihydroxycyclo-hex-3-en-1-yl)methyl benzoate (CAS 78804-17-8)
- 2-Amino-6-(hydroxymethyl)-4-(3-methoxy-4-propoxyphenyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carbonitrile (CAS 664999-51-3)
- (E)-2,6-dioxocyclohexane-1-carbaldehyde O-(2-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-2-oxoethyl) oxime (CAS 303150-04-1)
- n-(3-Chlorobenzyl)-1-methyl-1h-pyrazol-3-amine (CAS 1183511-53-6)
- (2-Bromo-6-(difluoromethyl)-3-nitropyridin-4-yl)methanamine (CAS 1805378-37-3)
- 5-Hydroxy-2-nitrobenzonitrile (CAS 13589-74-7)
- 2-(pyridin-2-yl)-1H-1,3-benzodiazol-5-amine dihydrochloride (CAS 1311316-12-7)
- 4-Bromo-3,5-dichlorobenzoic acid (CAS 117738-75-7)
- 6-Fluoro-4-nitro-2,3-dihydro-1H-inden-5-yl trifluoromethanesulfonate (CAS 2676865-59-9)
- n-[4-(2-aminoethoxy)phenyl]-N-methanesulfonylmethanesulfonamide hydrochloride (CAS 1432680-63-1)
- Verteporfin Impurity 7 (CAS CATO-C4X-35497)
- Pancreatic Polypeptide (1-17)-(Ala31,Aib32)-Neuropeptide Y (18-36) (human) trifluoroacetate salt (CAS 313988-70-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com