5-Hydroxy-3-methyl-1,2,4-oxadiazole CAS 52386-40-0
| CAS No. | 52386-40-0 |
| Molecular Formula | C3H4N2O2 |
| Molecular Weight | 100.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Hydroxy-3-methyl-1,2,4-oxadiazole.
5-Hydroxy-3-methyl-1,2,4-oxadiazole (CAS 52386-40-0) is a high-purity analytical reference standard with the molecular formula C3H4N2O2 and a molecular weight of 100.08 g/mol.
5-Hydroxy-3-methyl-1,2,4-oxadiazole (C3H4N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Hydroxy-3-methyl-1,2,4-oxadiazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C3H4N2O2 |
| Molecular Weight | 100.08 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1971 |
| Nitrogen Atoms | 2 |
Related Hydroxy Standards
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Recommended Standards
- 5-Aminoisoxazol-3(2H)-one (CAS 822-63-9)
- 5-Methyl-1,3,4-oxadiazol-2(3H)-one (CAS 3069-67-8)
- Pyrazolidine-3,5-dione (CAS 4744-71-2)
- Tetrazole-5-methanol (CAS 80251-76-9)
- 2-(2-Bromo-4-chlorophenoxy)cyclopentan-1-one (CAS 1234845-07-8)
- alpha-Cyclobutylbenzylamine Hydrochloride (CAS 58271-61-7)
- 1-Docosanol (CAS 661-19-8)
- 1-(Bromomethyl)-1-(2-ethoxyethyl)cyclopropane (CAS 1479556-02-9)
- 4-(Dimethylamino)-3-fluorophenol (CAS 1243354-90-6)
- Edoxaban Impurity 145 (CAS CATO-C4X-1063145)
- 4-Bromo-2-methyl-1-(2-methylpropoxy)benzene (CAS 1309933-10-5)
- 2-((3-Ethyl-4-oxo-3,4-dihydroquinazolin-2-yl)thio)acetic acid (CAS 462067-13-6)
- Linagliptin Impurity 13 (CAS 2742623-47-6)
- Semaglutide Impurity 123 (CAS 71997-93-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com