5-Aminoisoxazol-3(2H)-one CAS 822-63-9
| CAS No. | 822-63-9 |
| Molecular Formula | C3H4N2O2 |
| Molecular Weight | 100.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-Aminoisoxazol-3(2H)-one (C3H4N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 5-Aminoisoxazol-3(2H)-one (CAS 822-63-9), a certified reference material (molecular formula C3H4N2O2, MW 100.08 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C3H4N2O2 |
| Molecular Weight | 100.08 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related Aminoisoxazol Standards
- 1-(5-Aminoisoxazol-3-yl)ethanone (CAS 1558335-05-9)
- 2-Acetyl-5-aminoisoxazol-3(2H)-one (CAS 1573547-89-3)
- 2-(5-Aminoisoxazol-3-yl)-2-methylpropan-1-ol (CAS 1188910-70-4)
- 2-(5-Aminoisoxazol-3-yl)butan-2-ol (CAS 134965-78-9)
- 2-(3-Aminoisoxazol-5-yl)-2-methylpropan-1-ol (CAS 86860-67-5)
- Methyl 3-(5-aminoisoxazol-3-yl)propanoate (CAS 485807-07-6)
- 2-(5-Aminoisoxazol-3-yl)phenol (CAS 59899-13-7)
- 3-(5-Aminoisoxazol-3-yl)phenol (CAS 887591-58-4)
Recommended Standards
- 4-Hydroxy-1H-pyrazol-3(2H)-one (CAS 53666-86-7)
- 5-Hydroxy-3-methyl-1,2,4-oxadiazole (CAS 52386-40-0)
- 3-Hydroxy-4-methyl-1,2,5-oxadiazole (CAS 292856-44-1)
- 5-Methyl-1,3,4-oxadiazol-2(3H)-one (CAS 3069-67-8)
- 5-Cyclopropoxy-4-methylpicolinamide (CAS 1243355-63-6)
- methyl (2R)-2-(tert-butoxycarbonylamino)-4-iodo-butanoate (CAS 219752-75-7)
- 1-(3-Fluorophenyl)cyclohexan-1-amine hydrochloride (CAS 125802-18-8)
- Pimavanserin Impurity 18 (CAS CATO-C4X-193818)
- 3-(2-ethoxy-2-oxoethoxy)benzoic acid (CAS 1016826-94-0)
- (S)-1-(4-Methyl-3-nitrophenyl)ethan-1-amine (CAS 1241683-30-6)
- 2-Chloro-N-(2-chloroethyl)-N-(3-iodobenzyl)ethan-1-amine (CAS 40372-95-0)
- Methyl 2,4,4-trimethyl-1-oxaspiro[2.4]heptane-2-carboxylate (CAS 1502088-23-4)
- 5-Bromo-2-methoxybenzenesulfonamide (CAS 23095-14-9)
- Glucagon (19-29) (human, rat, porcine) (CAS 64790-15-4)
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