Naltrexone Impurity N96 CAS 52446-24-9
| CAS No. | 52446-24-9 |
| Molecular Formula | C16H17NO4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Naltrexone Impurity N96 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Naltrexone Impurity N96 (CAS 52446-24-9), a pharmacopoeial impurity reference standard (molecular formula C16H17NO4HCl, MW 323.77 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Naltrexone Impurity N96 (C16H17NO4HCl) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 323.77 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C16H17NO4 HCl |
| Molecular Weight | 323.77 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Naltrexone Standards
- Naltrexone EP Impurity A (CAS 1007856-83-8)
- Naltrexone Impurity 23 (CAS 102272-79-7)
- Naltrexone Impurity 15 (CAS 111129-14-7)
- Naltrexone impurity 30 (CAS 112242-13-4)
- Naltrexone Impurity 19 (CAS 112269-62-2)
- Naltrexone Impurity 13 (CAS 1201-90-7)
- Naltrexone Impurity 11 (CAS 123086-68-0)
- Naltrexone-D3 (CAS 1261080-26-5)
Recommended Standards
- Polymyxin Impurity 28 (CAS CATO-C4X-225528)
- Etoricoxib impurity 68 (CAS 58058-86-9)
- Citalopram Impurity 65 (CAS CATO-C4X-110965)
- 6-(1-Methyl-1H-pyrazol-4-yl)pyridazin-3-amine (CAS 1185767-30-9)
- 4-(((Tert-butoxycarbonyl)amino)methyl)cubane-1-carboxylic acid (CAS 2109516-33-6)
- 4'-fluoro-1',2'-dihydrospiro[cyclopentane-1,3'-indole] (CAS 1235439-61-8)
- 3-Isobutyl-2-mercapto-6-phenylthieno[2,3-d]pyrimidin-4(3h)-one (CAS 735319-20-7)
- 3-Chloro-5-(chlorosulfonyl)-4-methylbenzoic acid (CAS 1341830-84-9)
- 1-(6-Methyl-3-pyridinyl)ethanol-d4 (CAS 1346600-72-3)
- Compstatin control peptide (CAS 301544-78-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com