Pemetrexed Impurity 26 CAS 52454-78-1
| CAS No. | 52454-78-1 |
| Molecular Formula | C7H13NO4 |
| Molecular Weight | 175.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Pemetrexed Impurity 26 is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Pemetrexed Impurity 26 (CAS 52454-78-1, C7H13NO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Pemetrexed Impurity 26 (C7H13NO4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Pemetrexed Impurity 26 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H13NO4 |
| Molecular Weight | 175.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1971 |
| Nitrogen Atoms | 1 |
Related Pemetrexed Standards
- Pemetrexed Impurity 64 (CAS 65906-68-5)
- Pemetrexed Impurity 22 (CAS 1075-59-8)
- Pemetrexed Impurity (CAS 58973-64-1)
- Pemetrexed Impurity 39 (CAS 89113-43-9)
- Pemetrexed Impurity 10 (CAS 151864-81-2)
- Pemetrexed Impurity (CAS CATO-C4X-172640)
- Pemetrexed Impurity 42 (CAS 912935-56-9)
- Pemetrexed Impurity 75 (CAS 240407-05-0)
Recommended Standards
- Ketoprofen Impurity 72 (CAS CATO-C4X-147172)
- Voglibose Impurity 6 (CAS 38231-86-6)
- Ketoprofen EP Impurity G (CAS 5537-71-3)
- Procaterol Impurity 15 (CAS 22614-69-3)
- Flomoxef Impurity 46 (CAS CATO-C4X-138246)
- Salbutamol Impurity 85 (CAS 115787-52-5（free base）)
- Moxifloxacin(R,R)-Nonane (CAS 151213-42-2)
- Difamilast Impurity 3 (CAS 937782-02-0)
- 2,3-Dimethylimidazo[2,1-b]thiazole-5-carboxylic acid (CAS 1007875-84-4)
- TPBM (CAS 6466-43-9)
- 8-Bromoquinolin-7-amine (CAS 208512-63-4)
- 8-Bromo-1,3,4,5-tetrahydrothiopyrano[4,3-b]indole 2,2-dioxide (CAS 1465009-25-9)
- 6-Iodochroman-4-amine (CAS 676133-39-4)
- Tau Peptide (273-284) trifluoroacetate salt (CAS 1663490-91-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com