7,8-Dimethoxy-1,2,3,4-tetrahydroisoquinoline CAS 52759-08-7
| CAS No. | 52759-08-7 |
| Molecular Formula | C11H15NO2 |
| Molecular Weight | 193.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 7,8-Dimethoxy-1,2,3,4-tetrahydroisoquinoline (C11H15NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
7,8-Dimethoxy-1,2,3,4-tetrahydroisoquinoline (CAS 52759-08-7), molecular formula C11H15NO2 and molecular weight 193.24 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 7,8-Dimethoxy-1,2,3,4-tetrahydroisoquinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H15NO2 |
| Molecular Weight | 193.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Nitrogen Atoms | 1 |
Related Dimethoxy Standards
- 3,4-Dimethoxy-7-methylbicyclo[4.2.0]Octa-1,3,5-trien-7-amine (CAS 1128112-24-2)
- 5,6-Dimethoxy-2-methylisoindoline (CAS 114041-11-1)
- (S)-5,6-DIMETHOXY-2,3-DIHYDRO-1H-INDEN-1-AMINE (CAS 1260588-95-1)
- (R)-5,6-DIMETHOXY-2,3-DIHYDRO-1H-INDEN-1-AMINE (CAS 1260590-97-3)
- (S)-3,4-Dimethoxy-N-methylbicyclo[4.2.0]octa-1,3,5-trien-7-amine (CAS 1630795-79-7)
- 4,5-Dimethoxy-2,3-dihydro-1H-inden-1-amine (CAS 168902-80-5)
- 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline (CAS 1745-07-9)
- 4,7-Dimethoxy-2,3-dihydro-1H-inden-1-amine (CAS 763867-86-3)
Recommended Standards
- 6-Methylphenanthridine (CAS 3955-65-5)
- 7-Methoxy-1-methyl-1,2,3,4-tetrahydroisoquinolin-6-ol (CAS 76419-97-1)
- 6-Methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-ol (CAS 450-14-6)
- 8-Amino-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-4-ol (CAS 2126161-11-1)
- 4-Cyclopropoxy-3-methoxybenzenesulfonamide (CAS 1243368-31-1)
- 2,5-Dioxopyrrolidin-1-yl 6-((methylsulfonothioyl)oxy)hexanoate (CAS 76078-81-4)
- (1-(3-Methylbenzyl)piperidin-4-yl)methanamine (CAS 838814-74-7)
- 5-Bromo-2-chloro-N,N-diethylnicotinamide (CAS 1248914-99-9)
- (8-Hydroxy-3,4-dihydroquinolin-1(2H)-yl)(pyridin-3-yl)methanone (CAS 77771-22-3)
- 4-(Diethylamino)-2-methylquinoline-5,8-diol (CAS 88484-75-7)
- methyl 2-[4-(methylamino)phenoxy]acetate hydrochloride (CAS 1461714-23-7)
- Tetramethylammonium hydrogencarbonate (CAS 58345-96-3)
- (R)-3-Amino-4-(2-(trifluoromethyl)phenyl)butanoic acid (CAS 269396-76-1)
- Galanin (1-13)-Neuropeptide Y (25-36) amide (CAS 147138-51-0)
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