6-Methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-ol CAS 450-14-6
| CAS No. | 450-14-6 |
| Molecular Formula | C11H15NO2 |
| Molecular Weight | 193.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 193.24 g/mol gives 6-Methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-ol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
6-Methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-ol (CAS 450-14-6), molecular formula C11H15NO2 and molecular weight 193.24 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-ol (C11H15NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H15NO2 |
| Molecular Weight | 193.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Methoxy Standards
- (R)-7-Methoxy-1-methyl-1,2,3,4-tetrahydroisoquinolin-6-ol (CAS 101467-40-7)
- 2-Methoxy-5-{[(prop-2-en-1-yl)amino]methyl}phenol (CAS 1019561-00-2)
- 2-Methoxy-4-{[(prop-2-en-1-yl)amino]methyl}phenol (CAS 1019611-85-8)
- 9-Methoxy-2,3,4,5-tetrahydrobenzo[b]oxepin-5-amine (CAS 1094269-46-1)
- 8-Methoxy-6-methylchroman-4-amine (CAS 1094288-78-4)
- (S)-5-methoxy-2-(pyrrolidin-2-yl)phenol (CAS 1213163-04-2)
- (R)-5-methoxy-2-(pyrrolidin-2-yl)phenol (CAS 1213844-62-2)
- N-Methoxy-N,2,4-trimethylbenzamide (CAS 1221346-39-9)
Recommended Standards
- 6-Methoxy-1-methyl-1,2,3,4-tetrahydroisoquinolin-7-ol (CAS 4593-97-9)
- 6-Methylphenanthridine (CAS 3955-65-5)
- 6-ethoxy-3,4-dihydro-2H-1-benzopyran-4-amine (CAS 927970-57-8)
- 7,8-Dimethoxy-1,2,3,4-tetrahydroisoquinoline (CAS 52759-08-7)
- N-((1-Isobutyl-1H-pyrazol-4-yl)methyl)propan-1-amine hydrochloride (CAS 1855944-49-8)
- 5,7-Dichloro-2-fluoropyrazolo[1,5-a]pyrimidine (CAS 1159196-39-0)
- Methyl 2-(dimethylphosphoryl)benzoate (CAS 79317-60-5)
- henylephrine Impurity 42 (CAS 73898-35-8)
- 4-Allyl-2-ethoxy-1-methoxybenzene (CAS 155583-46-3)
- Nε-(1-Carboxyethyl)-L-lysine，Mixture of Diastereomers (CAS 5746-03-2)
- 2-(Cyclobutoxy)acetic Acid (CAS 189956-41-0)
- 1-[(4-bromophenyl)methyl]cyclopropan-1-ol (CAS 1247169-35-2)
- 7-tert-Butyl 2-methyl 4-oxo-4,5,6,8-tetrahydropyrido[3,4-d]pyrimidine-2,7(1H)-dicarboxylate (CAS 2561484-71-5)
- Semaglutide Impurity 157 (x TFA Salt) (CAS CATO-C4X-2226157)
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