1-(Difluoromethyl)-2-oxopyrrolidine-3-carboxylic acid CAS 1586813-24-2
| CAS No. | 1586813-24-2 |
| Molecular Formula | C6H7F2NO3 |
| Molecular Weight | 179.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(Difluoromethyl)-2-oxopyrrolidine-3-carboxylic acid is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(Difluoromethyl)-2-oxopyrrolidine-3-carboxylic acid (CAS 1586813-24-2) is a high-purity analytical reference standard with the molecular formula C6H7F2NO3 and a molecular weight of 179.12 g/mol.
Based on its molecular formula C6H7F2NO3, 1-(Difluoromethyl)-2-oxopyrrolidine-3-carboxylic acid contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 179.12 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H7F2NO3 |
| Molecular Weight | 179.12 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)-5-oxopyrrolidine-2-carboxylic acid (CAS 95755-28-5)
- 2-(Difluoromethyl)-4,5-difluoro-3-methylpyridine (CAS 1803672-95-8)
- 2-(Difluoromethyl)-3,5-difluoroaniline (CAS 1804417-60-4)
- 4-(difluoromethyl)-1,3-thiazole-5-carboxylic acid (CAS 2007917-53-3)
- 4-(Difluoromethyl)-2-fluoropyridine-3,5-diol (CAS 1805005-33-7)
- 2-(Difluoromethyl)-3,5-dihydroxy-4-fluoropyridine (CAS 1806796-98-4)
- 2-(Difluoromethyl)-3,6-dihydroxy-5-fluoropyridine (CAS 1806912-65-1)
- 5-(difluoromethyl)pyridine-2-carboxylic acid (CAS 859538-41-3)
Recommended Standards
- Ethyl 3-azido-2,2-difluoropropanoate (CAS 1403948-00-4)
- 4,4-Difluoro-1-methyl-5-oxopyrrolidine-3-carboxylic acid (CAS 1782418-67-0)
- 4-Fluoro-2-(trifluoromethyl)aniline (CAS 393-39-5)
- (2S,4S)-4-(difluoromethyl)-5-oxopyrrolidine-2-carboxylic acid (CAS 527705-01-7)
- Methyl 3-bromo-4-chloro-2-fluorobenzoate (CAS 1804897-28-6)
- 3-Iodo-4-(tert-pentyl)benzoic acid (CAS 1131588-21-0)
- N1,N4-Bis(4-bromophenyl)-N1,N4-diphenyl-1,4-benzenediamine (CAS 525602-17-9)
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- 3-(5-Methylfuran-2-carbonyl)-N-(5-methylthiazol-2-yl)thiazolidine-4-carboxamide (CAS 1281683-44-0)
- 2-(1,3-Benzodioxol-5-yl)-8-methylquinoline-4-carbonyl chloride (CAS 1160254-75-0)
- Guanidine, N-cyano-, polymer with N1-(2-aminoethyl)-1,2-ethanediamine, hydrochloride, cupric chloride complexes (CAS 70983-56-1)
- Methyl 1-(oxetan-3-yl)-1H-1,2,3-triazole-4-carboxylate (CAS 1707393-35-8)
- Di-tert-butyl (((9H-fluoren-9-yl)methoxy)carbonyl)-L-aspartate (CAS 129460-17-9)
- Insulin B (22-25) (CAS 34367-73-2)
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