2-(4-Chlorophenyl)-5’-fluoro-2’-hydroxyacetophenone CAS 527751-48-0

Purity 97%+In StockPharmaceutical Standards
CAS No.527751-48-0
Molecular FormulaC14H10ClFO2
Molecular Weight264.68 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(4-Chlorophenyl)-5’-fluoro-2’-hydroxyacetophenone CAS 527751-48-0 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 264.68 g/mol gives 2-(4-Chlorophenyl)-5’-fluoro-2’-hydroxyacetophenone distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 2-(4-Chlorophenyl)-5’-fluoro-2’-hydroxyacetophenone (CAS 527751-48-0), a certified reference material (molecular formula C14H10ClFO2, MW 264.68 g/mol) for analytical method development and quality control.

Structurally, 2-(4-Chlorophenyl)-5’-fluoro-2’-hydroxyacetophenone (C14H10ClFO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 264.68 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(4-Chlorophenyl)-5’-fluoro-2’-hydroxyacetophenone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H10ClFO2
Molecular Weight264.68 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1984
Halogen ContentF/Cl-containing

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