Phenylbutyrate EP Impurity B CAS 529-34-0

Purity >90%In StockPharmacopoeial Impurity Standards
CAS No.529-34-0
Molecular FormulaC10H10O
Molecular Weight146.19 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Phenylbutyrate EP Impurity B CAS 529-34-0 chemical structure

Description

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO supplies Phenylbutyrate EP Impurity B (CAS 529-34-0), a pharmacopoeial impurity reference standard (molecular formula C10H10O, MW 146.19 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Phenylbutyrate EP Impurity B (C10H10O) is characterized by a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H10O
Molecular Weight146.19 g/mol
Purity>90%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957

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