Digoxin EP Impurity F CAS 5297-05-2
| CAS No. | 5297-05-2 |
| Molecular Formula | C35H54O11 |
| Molecular Weight | 650.80 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system, Digoxin EP Impurity F is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 650.80 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Digoxin EP Impurity F (CAS 5297-05-2) is a certified pharmaceutical impurity reference standard with the molecular formula C35H54O11 and a molecular weight of 650.80 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Digoxin EP Impurity F meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C35H54O11 |
| Molecular Weight | 650.80 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Digoxin Standards
Recommended Standards
- Enzyme-IN-1 (CAS 868540-02-7)
- N-(9,9-diphenyl-9H-fluoren-2-yl)-N,9-diphenyl-9H-carbazol-2-amine (CAS 1607480-22-7)
- 2,6-Bis(methylthio)pyrimidine-4-carboxylic acid (CAS 90151-13-6)
- 2,2'-Bis(diphenylamino)-9,9'-spirobifluorene (CAS 862664-73-1)
- Candesartan Cilexetil Impurity 32 (CAS 62351-79-5)
- Ruxolitinib Impurity 37 (CAS 2821844-77-1)
- Dotinurad Impurity 81 (CAS 82848-00-8)
- 4,4'-Bis((2-methyl-1H-imidazol-1-yl)methyl)-1,1'-biphenyl (CAS 1283072-03-6)
- n-Cycloheptyl-4-methylpyridin-3-amine (CAS 1338991-06-2)
- 1-(Difluoromethyl)-N-(3-fluorobenzyl)-3-methyl-1H-pyrazol-4-amine hydrochloride (CAS 1855950-76-3)
- [1-(5-Methoxypyridin-2-yl)cyclopropyl]methanamine dihydrochloride (CAS 1439897-91-2)
- Dasatinib Impurity 66 (CAS 2468737-89-3)
- n-(2-Chloro-6-iodo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)pivalamide (CAS 1357387-98-4)
- D-Ala21-Tirzepatide (CAS CATO-CPTD788913)
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