Lumefantrine Impurity 5 CAS 69759-61-1
| CAS No. | 69759-61-1 |
| Molecular Formula | C23H29Cl2NO |
| Molecular Weight | 406.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Lumefantrine Impurity 5 (CAS 69759-61-1, C23H29Cl2NO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Lumefantrine Impurity 5 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 406.39 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H29Cl2NO |
| Molecular Weight | 406.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Lumefantrine Standards
- Lumefantrine Impurity 11 (CAS CATO-C4X-242611)
- Lumefantrine Impurity 3 (CAS 4364-35-6)
- Lumefantrine Impurity 6 (CAS 355841-11-1)
- Lumefantrine impurity 7 (CAS CATO-C4X-24267)
- (9E)-Lumefantrine (CAS 1456736-33-6)
- LUMEFANTRINE (CAS 204133-10-8)
- Lumefantrine Impurity 1 (CAS 1331642-68-2)
- Lumefantrine Impurity 14 (CAS 2170653-95-7)
Recommended Standards
- Gadodiamide Impurity 1 (CAS 137076-43-8)
- Camptothecin impurity 18 (CAS 19685-11-1)
- Suc-Ala-Pro-pNA (CAS 95632-46-5)
- Azilsartan Impurity 128 (CAS CATO-C4X-1096128)
- Zopiclone Impurity 12 (CAS CATO-C4X-123812)
- Cefamandole Impurity 10 (CAS CATO-C4X-122110)
- Raloxifene Impurity 6 (CAS 2008-75-5)
- N/A (CAS CATO-CQCM104334)
- 1,8-Dimethoxy-3-methylanthracene-9,10-dione (CAS 71013-35-9)
- 1-(3-Fluorobenzyl)-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one (CAS 303988-05-8)
- 2-Methoxy-6-(p-tolyl)pyridine (CAS 1039775-38-6)
- Evocalcet Impurity 2 (CAS CATO-C4X-24852)
- 3NV4Z4Y7YV 507-36-8 tert-Amyl bromide 2-Bromo-2-methylbutane Butane, 2-bromo-2-methyl- AI3-17814 EINECS 208-071-1 2-Methyl-2-bromobutane NSC 7897 tert-Pentyl bromide UNII-3NV4Z4Y7YV (CAS 507-36-8)
- Des-Ala28-Tirzepatide (CAS CATO-CPTD788945)
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