Fluorouracil Impurity N1 CAS 5329-33-9

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.5329-33-9
Molecular FormulaC2H6N2O
Molecular WeightN/A
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Fluorouracil Impurity N1 CAS 5329-33-9 chemical structure

Description

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO supplies Fluorouracil Impurity N1 (CAS 5329-33-9), a pharmacopoeial impurity reference standard (molecular formula C2H6N2OHCl, MW 110.54 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Fluorouracil Impurity N1 (C2H6N2OHCl) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC2H6N2O HCl
Molecular Weight110.54 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)0.0
CAS Registry Year (est.)1958
Halogen ContentCl-containing
Nitrogen Atoms2

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