2-Chloro-5-(trifluoromethyl)-1,3,4-thiadiazole CAS 53645-98-0
| CAS No. | 53645-98-0 |
| Molecular Formula | C3ClF3N2S |
| Molecular Weight | 188.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 188.56 g/mol gives 2-Chloro-5-(trifluoromethyl)-1,3,4-thiadiazole distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Chloro-5-(trifluoromethyl)-1,3,4-thiadiazole (CAS 53645-98-0) is a high-purity analytical reference standard with the molecular formula C3ClF3N2S and a molecular weight of 188.56 g/mol.
2-Chloro-5-(trifluoromethyl)-1,3,4-thiadiazole (C3ClF3N2S) contains a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-5-(trifluoromethyl)-1,3,4-thiadiazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C3ClF3N2S |
| Molecular Weight | 188.56 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 3-Chloro-6,7-difluoro-1H-indazole (CAS 1000343-96-3)
- 2-Chloro-6,7-difluoro-1H-benzo[d]imidazole (CAS 1388061-00-4)
- 2-chloro-5,6-difluoro-1H-benzimidazole (CAS 142356-63-6)
- 2-Chloro-6-(difluoromethyl)nicotinonitrile (CAS 1662687-58-2)
- 2-Chloro-5-(difluoromethyl)nicotinonitrile (CAS 1803708-38-4)
- 4-Chloro-5-(difluoromethyl)nicotinonitrile (CAS 1804703-69-2)
- 6-Chloro-5-(difluoromethyl)picolinonitrile (CAS 1804754-02-6)
- 2-Chloro-4-(difluoromethyl)nicotinonitrile (CAS 1805032-46-5)
Recommended Standards
- 6-Chloro-4-(difluoromethyl)picolinonitrile (CAS 1806022-98-9)
- 5-Chloro-3-(trifluoromethyl)-1,2,4-thiadiazole (CAS 672-35-5)
- 6-Chloro-5-(difluoromethyl)nicotinonitrile (CAS 1805304-66-8)
- 5-Chloro-6,7-difluoro-1H-benzo[d]imidazole (CAS 217951-45-6)
- 4-Chloro-7-(trifluoromethoxy)quinoline (CAS 40516-31-2)
- Pyridazine-3,5-diamine (CAS 61071-13-4)
- 5-Bromoimidazo[2,1-b]thiazole (CAS 67088-53-3)
- 6-Hydroxy-2,3-dihydroindolizin-5(1H)-one (CAS 253195-68-5)
- 7-Methyl-1,2,3,4-tetrahydroquinoline hydrochloride (CAS 90874-58-1)
- 4-(3,4-Difluoro-phenyl)-4-oxo-but-2-enoic acid (CAS 83844-24-0)
- 1-Isopropyl-4-(6-nitropyridin-3-yl)piperazine (CAS 943758-04-1)
- 3-((4-Isopropylphenyl)amino)-1-(4-methoxyphenyl)propan-1-one (CAS 939893-48-8)
- 4-Amino-N-(pyridin-2-ylmethyl)benzenesulfonamide (CAS 294889-56-8)
- Tripeptide-10 citrulline (CAS 960531-53-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com