Apixaban Impurity 41 CAS 536760-29-9
| CAS No. | 536760-29-9 |
| Molecular Formula | C11H9ClN2O3 |
| Molecular Weight | 252.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Apixaban Impurity 41 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Apixaban Impurity 41 (CAS 536760-29-9) is a certified pharmaceutical impurity reference standard with the molecular formula C11H9ClN2O3 and a molecular weight of 252.65 g/mol.
Structurally, Apixaban Impurity 41 (C11H9ClN2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 252.65 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C11H9ClN2O3 |
| Molecular Weight | 252.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Apixaban Standards
- Apixaban Impurity 101 (CAS 2219376-48-2)
- Apixaban Impurity 169 (CAS CATO-C4X-1088169)
- Apixaban Impurity 146 (CAS CATO-C4X-1088146)
- Apixaban Impurity 96 (CAS 2512213-45-3)
- Apixaban Impurity 42 (CAS 132577-23-2)
- Apixaban impurity 159 (CAS CATO-C4X-1088159)
- Apixaban Impurity 31 (CAS CATO-C4X-108831)
- Apixaban Impurity 99 (CAS 1802522-36-6)
Recommended Standards
- 3-Chloro-N-isobutyl-5-(trifluoromethyl)-2-pyridinamine (CAS 1036583-63-7)
- 660417-52-7 3-[3-(3-Chlorophenyl)-1,2,4-oxadiazol-5-yl]propanoic acid MFCD08133366 (CAS 660417-52-7)
- N-(sec-Butyl)-3-chloro-5-(trifluoromethyl)-2-pyridinamine (CAS 1036594-37-2)
- 0087AC 657424-68-5 C11H9ClN2O3 Ethyl 5-(3-chlorophenyl)-1,2,4-oxadiazole-3-carboxylate (CAS 657424-68-5)
- Clenbuterol EP impurity D (CAS 99-92-3)
- Atrasentan Impurity 7 (CAS 178608-09-8)
- Azacitidine Impurity 61 (CAS 18265-49-1)
- Argatroban (CAS CATO-C4X-1007104)
- 58048-37-6 2-(2,4-Dichlorophenoxy)propanoyl chloride DTXSID20558730 (CAS 58048-37-6)
- tert-butyl N-[1,3-dihydroxy-1-(pyridin-3-yl)propan-2-yl]carbamate (CAS 2059971-51-4)
- (2S,10R)-4,6-Diphenyl-8,12-dioxa-5,6-diazapentacyclo[11.8.0.0^{2,10}.0^{3,7}.0^{16,21}]henicosa-1(13),3(7),4,14,16(21),17,19-heptaene (CAS 317821-82-2)
- 1-[(E)-2-Phenylethenyl]-4-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline (CAS 338968-42-6)
- 1-Chloro-4-(3,3,3-trifluoroprop-1-en-2-yl)benzene (CAS 69843-10-3)
- Neuropeptide SF (human) (CAS 192387-39-6)
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