17β-Estradiol-2,4-d2 CAS 53866-33-4

Purity >95%In StockPharmaceutical Standards
CAS No.53866-33-4
Molecular Formula-
Molecular Weight274.39 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

17β-Estradiol-2,4-d2 CAS 53866-33-4 chemical structure

Description

The molecular framework of 17β-Estradiol-2,4-d2 (C18H22D2O2) is characterized by deuterium isotope labeling, a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

17β-Estradiol-2,4-d2 (CAS 53866-33-4) is a high-purity analytical reference standard with the molecular formula C18H22D2O2 and a molecular weight of 274.39 g/mol.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 17β-Estradiol-2,4-d2 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC18H22D2O2
Molecular Weight274.39 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1972

Related Estradiol Standards

Recommended Standards

Why CATO?