17alpha-Estradiol-2,4-d2 CAS 81586-94-9

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 17alpha-Estradiol-2,4-d2.

17alpha-Estradiol-2,4-d2 (CAS 81586-94-9) is a high-purity analytical reference standard with the molecular formula C18H22D2O2 and a molecular weight of 274.39 g/mol.

The molecular framework of 17alpha-Estradiol-2,4-d2 (C18H22D2O2) is characterized by deuterium isotope labeling, a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 17alpha-Estradiol-2,4-d2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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