Travoprost Impurity 18 CAS 53872-60-9
| CAS No. | 53872-60-9 |
| Molecular Formula | C18H19F3O5 |
| Molecular Weight | 372.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Travoprost Impurity 18 (C18H19F3O5) contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 372.34 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Travoprost Impurity 18 (CAS 53872-60-9), a pharmacopoeial impurity reference standard (molecular formula C18H19F3O5, MW 372.34 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H19F3O5 |
| Molecular Weight | 372.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | F-containing |
Related Travoprost Standards
- Travoprost Related Compound 25 (CAS CATO-C4X-192525)
- Travoprost Related Compound 26 (CAS CATO-C4X-192526)
- Travoprost Impurity 47 (CAS 1415385-39-5)
- Travoprost Impurity 60 (CAS 64998-32-9)
- Travoprost Impurity 50 (CAS 2218532-68-2)
- Travoprost Impurity 57 (CAS CATO-C4X-192557)
- Travoprost Impurity 52 (CAS CATO-C4X-192552)
- Travoprost Impurity 58 (CAS 2124200-60-6)
Recommended Standards
- Pentoxifylline EP Impurity E (CAS 77196-87-3)
- Doxofylline Impurity 15 (CAS CATO-C4X-151315)
- Sofosbuvir Impurity 46 (CAS 874638-80-9)
- Sofosbuvir Impurity 3 (CAS CATO-C4X-10523)
- Cholic Acid Impurity 4 (CAS CATO-C4X-11604)
- Alverine Impurity 15 HCl (CAS CATO-C4X-153915)
- Nefopam impurity 17 (CAS 82561-25-9)
- (3-Chloro-4-fluorophenyl)(thiophen-3-yl)methanol (CAS 1443341-83-0)
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- 1-(2-(Methylamino)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)ethan-1-one (CAS 2103352-44-7)
- Oxaliplatin Impurity 11 (CAS 61848-66-6)
- (E)-5-((2-chlorobenzyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde O-(2-chloroacetyl) oxime (CAS 321553-34-8)
- Ethyl 3-amino-1H-pyrrole-2-carboxylateHCl (CAS 252932-49-3)
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Why CATO?
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