Sofosbuvir Impurity 3 CAS CATO-C4X-10523
| CAS No. | CATO-C4X-10523 |
| Molecular Formula | C20H17FO6 |
| Molecular Weight | 372.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Sofosbuvir Impurity 3 (C20H17FO6) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Sofosbuvir Impurity 3 (CAS CATO-C4X-10523) is a certified pharmaceutical impurity reference standard with the molecular formula C20H17FO6 and a molecular weight of 372.34 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H17FO6 |
| Molecular Weight | 372.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Sofosbuvir Standards
- Sofosbuvir Impurity 1 (CAS 1033394-94-3)
- Sofosbuvir Impurity 105 (CAS 1946820-91-2)
- Sofosbuvir Impurity 2 (CAS 1157884-58-6)
- Sofosbuvir Impurity 46 (CAS 874638-80-9)
- Sofosbuvir Impurity 84 (CAS 914912-69-9)
- Sofosbuvir Impurity 43 (CAS CATO-C4X-105243)
- Sofosbuvir Impurity 60 (CAS CATO-C4X-105260)
- Sofosbuvir Impurity 80 (CAS CATO-C4X-105280)
Recommended Standards
- Doxofylline Impurity 15 (CAS CATO-C4X-151315)
- Pentoxifylline EP Impurity E (CAS 77196-87-3)
- N-benzyl-4-(3-(trifluoromethyl)benzoyl)-1H-pyrrole-2-carboxamide (CAS 478078-23-8)
- Travoprost Impurity 18 (CAS 53872-60-9)
- Daptomycin Impurity F (CAS CATO-C4X-137858)
- Solriamfetol Impurity 19 (CAS CATO-C4X-256319)
- Drotaverin Impurity 43 (CAS CATO-C4X-243543)
- 3-Fluoro-2-(pyrrolidin-1-yl)aniline (CAS 1233955-57-1)
- 2-Bromo-1,1,1-trifluoro-butane (CAS 31333-11-6)
- Ethyl 3-(furan-2-yl)-3-oxopropanoate (CAS 615-09-8)
- Agomelatine Impurity 4 (CAS CATO-C4X-11084)
- Tert-butyl (1-(azetidin-3-yl)-2-hydroxyethyl)carbamate (CAS 2168772-02-7)
- N-((1H-Indol-2-yl)methyl)-6-(5-amino-3-methyl-1H-pyrazol-1-yl)pyrimidin-4-amine (CAS 1808570-78-6)
- Semaglutide Impurity 11 (CAS CATO-C4X-222611)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com