Trimetazidine EP Impurity I(Dihydrochloride) CAS 53960-20-6
| CAS No. | 53960-20-6 |
| Molecular Formula | C15H24N2O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 316.83 g/mol gives Trimetazidine EP Impurity I(Dihydrochloride) distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Trimetazidine EP Impurity I(Dihydrochloride) (CAS 53960-20-6) is a certified pharmaceutical impurity reference standard with the molecular formula C15H24N2O3HCl and a molecular weight of 316.83 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Trimetazidine EP Impurity I(Dihydrochloride) is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 316.83 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Trimetazidine EP Impurity I(Dihydrochloride) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H24N2O3 2*HCl |
| Molecular Weight | 316.83 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Trimetazidine Standards
- Trimetazidine EP Impurity A DiHCl (CAS 107049-57-0)
- Trimetazidine EP Impurity G (CAS 110-85-0)
- Trimetazidine Impurity 5 (CAS 1133-49-9)
- Trimetazidine EP Impurity F（Dihydrochloride） (CAS 113698-83-2)
- Trimetazidine-D8 Dihydrochloride (CAS 1219795-37-5)
- Trimetazidine-d8 Dihydrochloride (CAS 1219908-67-4)
- Trimetazidine EP Impurity B (CAS 1257-19-8)
- Trimetazidine Dihydrochloride (CAS 13171-25-0)
Recommended Standards
- Mitomycin impurity 3 (CAS 99745-88-7)
- Revefenacin impurity 95 (CAS CATO-C4X-203195)
- Everolimus Impurity 2 (CAS 147438-30-0)
- Famoxadone (CAS 131807-57-3)
- 3-(4-Bromophenyl)-2,2-difluorocyclopropane-1-carboxylic acid (CAS 2098048-73-6)
- Iomeprol Impurity 19 (CAS CATO-C4X-182019)
- (4S,5R)-4-Formyl-2,2,5-trimethyl-3-oxazolidinecarboxylic Acid 1,1-Dimethylethyl Ester (CAS 108149-62-8)
- 2-((Benzyloxy)carbonyl)-2-azabicyclo[2.2.2]oct-7-ene-6-carboxylic acid (CAS 1253521-31-1)
- N-Isopropyl-5-(((thiophen-2-ylmethyl)amino)methyl)pyrimidin-2-amine (CAS 1279216-00-0)
- Delta-Sleep Inducing Peptide (CAS 62568-57-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com