1-(2-Chlorophenyl)-2-methylpropan-1-one CAS 5408-59-3
| CAS No. | 5408-59-3 |
| Molecular Formula | C10H11ClO |
| Molecular Weight | 182.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(2-Chlorophenyl)-2-methylpropan-1-one is closely related to a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1-(2-Chlorophenyl)-2-methylpropan-1-one (CAS 5408-59-3), a certified reference material (molecular formula C10H11ClO, MW 182.65 g/mol) for analytical method development and quality control.
The molecular framework of 1-(2-Chlorophenyl)-2-methylpropan-1-one (C10H11ClO) is characterized by a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11ClO |
| Molecular Weight | 182.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
Related Chlorophenyl Standards
- 1-(2-Chlorophenyl)butan-2-one (CAS 103040-37-5)
- 3-(3-Chlorophenyl)cyclobutanol (CAS 1178487-43-8)
- 1-(3-Chlorophenyl)butan-2-one (CAS 1181404-78-3)
- 3-(2-Chlorophenyl)cyclobutanol (CAS 1182960-42-4)
- 3-(4-Chlorophenyl)cyclobutan-1-ol (CAS 1184692-46-3)
- 2-(3-Chlorophenyl)-2-methylpropanal (CAS 1225521-01-6)
- (3-Chlorophenyl)(cyclopropyl)methanol (CAS 1225850-49-6)
- (2-(4-Chlorophenyl)cyclopropyl)methanol (CAS 1278662-50-2)
Recommended Standards
- 1-(2-Chloroallyl)-4-methoxybenzene (CAS 91284-04-7)
- 1-(2-Chlorophenyl)but-3-en-1-ol (CAS 24165-66-0)
- 1-(2-Chloroallyl)-3-methoxybenzene (CAS 731773-16-3)
- 1-(2-Chlorophenyl)butan-1-one (CAS 21550-07-2)
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