Pioglitazone impurity 28 CAS 5408-74-2
| CAS No. | 5408-74-2 |
| Molecular Formula | C9H11N |
| Molecular Weight | 133.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Pioglitazone impurity 28.
As a process- or degradation-related impurity, Pioglitazone impurity 28 (CAS 5408-74-2, C9H11N) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Pioglitazone impurity 28 (C9H11N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. Its physicochemical properties are representative of its class; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H11N |
| Molecular Weight | 133.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
Related Pioglitazone Standards
- Pioglitazone impurity 54 (CAS 54119-29-8)
- Pioglitazone impurity 59 (CAS 102438-88-0)
- Pioglitazone impurity 60 (CAS 1000564-06-6)
- Pioglitazone Impurity 14 (CAS 1526933-30-1)
- Pioglitazone Impurity 20 (CAS 69603-36-7)
- Pioglitazone Impurity 24 (CAS 127676-18-0)
- Pioglitazone Impurity 2 (CAS 69088-97-7)
- Pioglitazone impurity 56 (CAS 1258625-43-2)
Recommended Standards
- Metoprolol EP Impurity N (CAS 6452-57-9)
- Indapamide Impurity 22 (CAS 6872-06-6)
- Levocetirizine Impurity 50 (CAS 1074-42-6)
- Indapamide Impurity 32 (CAS 22160-09-4)
- Peficitinib Impurity 15-d3,15N (CAS CATO-C4X-280715)
- Dequalinium Impurity 7 (CAS 19056-26-9)
- Pranlukast Impurity 6 (CAS CATO-C4X-18046)
- (4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone (CAS 1360705-96-9)
- Baclofen impurity 10 (CAS 28311-33-3)
- 2,4-Bis(4-Fluorophenyl)-3,5-Diphenyl-2,4-Cyclopentadien-1-One (CAS 22818-67-3)
- N-1,3-Benzodioxol-5-yl-N-(ethylsulfonyl)glycine (CAS 1858256-04-8)
- N-n-Butyl-N-methylethanolamine (CAS 2893-48-3)
- 2-Bromo-N-[4-(isopentyloxy)phenyl]acetamide (CAS 1138445-89-2)
- Neuropeptide Y (1-24) amide (human, rat) (CAS 131448-51-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com