1-(5-Chloro-2,4-dimethoxyphenyl)ethan-1-one CAS 54173-36-3
| CAS No. | 54173-36-3 |
| Molecular Formula | C10H11ClO3 |
| Molecular Weight | 214.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(5-Chloro-2,4-dimethoxyphenyl)ethan-1-one.
1-(5-Chloro-2,4-dimethoxyphenyl)ethan-1-one (CAS 54173-36-3), molecular formula C10H11ClO3 and molecular weight 214.65 g/mol, is a CATO reference standard with documented purity and traceability.
1-(5-Chloro-2,4-dimethoxyphenyl)ethan-1-one (C10H11ClO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11ClO3 |
| Molecular Weight | 214.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 4-Chloro-1-cyclopentyl-1H-pyrazole-3-carboxylic acid (CAS 1006451-33-7)
- 2-(4-Chloro-3-cyclopropyl-1h-pyrazol-1-yl)propanoic acid (CAS 1006490-23-8)
- 4-Chloro-1-cyclopentyl-1h-pyrazole-5-carboxylic acid (CAS 1006493-95-3)
- 6-Chloro-N-(2-methoxyethyl)pyridine-3-carboxamide (CAS 1016741-22-2)
- 2-Chloro-5-phenylnicotinonitrile (CAS 10177-10-3)
- Ethyl 2-chloro-3-(methylamino)isonicotinate (CAS 1034132-15-4)
- 2-(2-Chloro-3,4-dimethoxyphenyl)acetaldehyde (CAS 103483-18-7)
- 2-Chloro-N-methoxy-N,6-dimethylnicotinamide (CAS 1057667-23-8)
Recommended Standards
- 1-(3-Chloro-4-methylphenyl)-3-methoxyurea (CAS 52420-57-2)
- 1-Chloro-9H-fluoren-9-one (CAS 36804-56-5)
- 1-(2-Chloro-5-nitrophenyl)-N,N-dimethylmethanamine (CAS 697305-62-7)
- 2-((5-Chloro-2-methoxyphenyl)amino)acetamide (CAS 923137-95-5)
- 4-Propyl-5-(pyridin-3-yl)-4H-1,2,4-triazole-3-thiol (CAS 90871-44-6)
- 4-Hydroxy-N-propylbenzamide (CAS 27519-68-2)
- 6-Amino-2-chloropyrimidine-4-carbonitrile (CAS 64376-18-7)
- 4-Chloroanilidophosphoryldichloride (CAS 6971-73-9)
- 2-(3,4-Dimethoxyphenyl)acetyl chloride (CAS 10313-60-7)
- 6-(3-methoxypiperidin-1-yl)pyridin-3-amine (CAS 939376-71-3)
- 2-Propenoic acid, 2-methyl-, polymer with ethenylbenzene, potassium salt (CAS 25068-00-2)
- 2-(2-Mercapto-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)-N-(4-methoxyphenyl)acetamide (CAS 1142206-71-0)
- 1-(But-3-en-1-yl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CAS 1339035-07-2)
- Semaglutide impurity 77 (CAS CATO-C4X-222677)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com