Nimesulide EP Impurity D CAS 5422-92-4
| CAS No. | 5422-92-4 |
| Molecular Formula | C12H10N2O3 |
| Molecular Weight | 230.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Nimesulide EP Impurity D under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Nimesulide EP Impurity D (CAS 5422-92-4), a pharmacopoeial impurity reference standard (molecular formula C12H10N2O3, MW 230.22 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Nimesulide EP Impurity D (C12H10N2O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C12H10N2O3 |
| Molecular Weight | 230.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
Related Nimesulide Standards
- Nimesulide EP Impurity G (CAS 70995-08-3)
- Nimesulide Impurity 2 (CAS 38880-53-4)
- Nimesulide Impurity 8 (CAS 2216-12-8)
- Nimesulide EP Impurity B (CAS 51765-51-6)
- Nimesulide Impurity N1 (CAS 19881-18-6)
- Nimesulide EP Impurity C (CAS 2688-84-8)
- Nimesulide (CAS 51803-78-2)
- Nimesulide EP Impurity E (CAS 905858-63-1)
Recommended Standards
- Sodium aminosalicylate Impurity 4 (CAS 17540-51-1)
- Nicotinamide Impurity 12 (CAS CATO-C4X-200012)
- Acetaminophen Impurity 41 (CAS CATO-C4X-121141)
- Dexrazoxane Impurity 21 (CAS CATO-C4X-202021)
- Daptomycin Impurity 46 (CAS CATO-C4X-137846)
- Progesterone Impurity 38 (CAS 19289-77-1)
- Primidone EP Impurity E (CAS 90-27-7)
- 3-(Boc-amino)-2-butanol (CAS 752135-63-0)
- Pyrido[2,3-b]pyrazine-7-carboxylic acid (CAS 893723-49-4)
- 2-methyl-3-(1,3-oxazol-2-yl)aniline hydrochloride (CAS 1803603-70-4)
- 4,4′′′-Diiodo-1,1′:4′,1′′:4′′,1′′′-quaterphenyl (CAS 1770-82-7)
- 2-oxabicyclo[2.1.1]hexan-4-amine;hydrochloride (CAS 2260936-52-3)
- 6-(Cyclohex-2-en-1-yl)hexanoic acid (CAS 2105-35-3)
- Tirzepatide Impurity 9 (CAS CATO-C4X-32409)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com