Nimesulide EP Impurity G CAS 70995-08-3
| CAS No. | 70995-08-3 |
| Molecular Formula | C12H9NO4 |
| Molecular Weight | 231.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Nimesulide EP Impurity G (CAS 70995-08-3, C12H9NO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Nimesulide EP Impurity G (C12H9NO4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Nimesulide EP Impurity G under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H9NO4 |
| Molecular Weight | 231.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Nitrogen Atoms | 1 |
Related Nimesulide Standards
- Nimesulide EP Impurity D (CAS 5422-92-4)
- Nimesulide Impurity 2 (CAS 38880-53-4)
- Nimesulide Impurity 8 (CAS 2216-12-8)
- Nimesulide EP Impurity B (CAS 51765-51-6)
- Nimesulide Impurity N1 (CAS 19881-18-6)
- Nimesulide EP Impurity C (CAS 2688-84-8)
- Nimesulide (CAS 51803-78-2)
- Nimesulide EP Impurity E (CAS 905858-63-1)
Recommended Standards
- 2,3-Dioxo-glutaric Acid Diethyl Ester 2-Oxime 2-(Hydroxyimino)-3-oxo-pentanedioic Acid 1,5-Diethyl Ester 2-(Hydroxyimino)-3-oxo-pentanedioic Acid Diethyl Ester 996-75-8 (CAS 996-75-8)
- Iguratimod Impurity 82 (CAS CATO-C4X-182682)
- 4756AE 51726-78-4 7-Acetyl-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid C12H9NO4 (CAS 51726-78-4)
- 3-Hydrazineyl-6-(3-nitrophenyl)pyridazine (CAS 1017117-06-4)
- Difelikefalin Impurity 8 Trifluoroacetic acid (CAS CATO-C4X-30418)
- Pentoxifylline Impurity 14 (CAS 6493-07-8)
- Bromfenac Impurity 43 (CAS CATO-C4X-200243)
- Ethyl 5-amino-6-chloro-2-methylpyrimidine-4-carboxylate (CAS 1393541-06-4)
- Benzyl (5R,7S)-4-hydroxy-7-methyl-2-oxo-1,8-diazaspiro[4.5]Decane-8-carboxylate (CAS 1227685-24-6)
- Carbonyl-¹³C sulfide (CAS 6142-96-7)
- 4154AF 946786-99-8 C10H22N2O N,N-Dimethyl-2-(3-piperidinylmethoxy)-1-ethanamine (CAS 946786-99-8)
- (3,5-Dioxo-morpholin-4-yl)-acetic acid (CAS 938459-18-8)
- Perfluoro(4-methylpent-2-ene) (CAS 2070-70-4)
- Cholecystokinin Octapeptide (sulfated) (H-2060.0005) (CAS 25679-23-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com