Nimesulide EP Impurity E CAS 905858-63-1
| CAS No. | 905858-63-1 |
| Molecular Formula | C14H15NO5S2 |
| Molecular Weight | 341.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Nimesulide EP Impurity E (CAS 905858-63-1) is a certified pharmaceutical impurity reference standard with the molecular formula C14H15NO5S2 and a molecular weight of 341.40 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Nimesulide EP Impurity E is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 341.40 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C14H15NO5S2 |
| Molecular Weight | 341.40 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Nimesulide Standards
- Nimesulide EP Impurity A (CAS 51765-56-1)
- Nimesulide (CAS 51803-78-2)
- Nimesulide EP Impurity F (CAS 51765-72-1)
- Nimesulide Impurity N1 (CAS 19881-18-6)
- Nimesulide EP Impurity B (CAS 51765-51-6)
- Nimesulide Impurity 2 (CAS 38880-53-4)
- Nimesulide EP Impurity G (CAS 70995-08-3)
- Nimesulide EP Impurity D (CAS 5422-92-4)
Recommended Standards
- Naltrexone impurity 49 (CAS CATO-C4X-147549)
- Naloxone Impurity 18 (CAS CATO-C4X-149318)
- Naltrexone EP Impurity C (CAS 189016-90-8)
- Naloxone EP Impurity G (CAS 70866-64-7)
- Amiodarone Impurity 23 (CAS CATO-C4X-142523)
- Levetiracetam Impurity 37 (CAS 1847568-87-9)
- Peramivir Impurity 29 ·0.1Formate (CAS CATO-C4X-183365)
- Rizatriptan Impurity 15 (CAS 6085-94-5)
- 6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanehydrazide hydrochloride (CAS 175290-73-0)
- 5-Methyl-1-(quinolin-6-yl)-1h-1,2,3-triazole-4-carboxylic acid (CAS 1269151-91-8)
- N-(2-((2-Aminoethyl)(isopropyl)amino)cyclohexyl)acetamide (CAS 1353968-13-4)
- 2,3,4-Tri-O-acetyl-α-D-arabinopyranosyl isothiocyanate (CAS 62414-75-9)
- (R)-2-Amino-1-(piperidin-1-yl)propan-1-one hydrochloride (CAS 720001-82-1)
- Liraglutide(3-31)TFA Salt (CAS CATO-C4X-19921)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com