Noradrenaline EP Impurity E CAS 54234-59-2
| CAS No. | 54234-59-2 |
| Molecular Formula | C8H7ClO3 |
| Molecular Weight | 186.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Noradrenaline EP Impurity E (CAS 54234-59-2), a pharmacopoeial impurity reference standard (molecular formula C8H7ClO3, MW 186.59 g/mol) used for the identification and quantification of trace impurities in APIs.
Noradrenaline EP Impurity E (C8H7ClO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Noradrenaline EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7ClO3 |
| Molecular Weight | 186.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
Related Noradrenaline Standards
- Noradrenaline EP Impurity E (CAS 99-40-1)
- Noradrenaline RC 1 (Base) (CAS 97-31-4)
- L-Noradrenaline (CAS 51-41-2)
- Noradrenaline(Norepinephrine) Impurity 68 (CAS 67083-58-3)
- l-Noradrenaline tartrate (CAS 51-40-1)
- Noradrenaline Hydrochloride EP Impurity B (CAS 5090-29-9)
- Noradrenaline bitartrate (CAS 69815-49-2)
- L-Noradrenaline Bitartrate Monohydrate (CAS 108341-18-0)
Recommended Standards
- Methyl 4-chloro-2-hydroxybenzoate (CAS 22717-55-1)
- (S)-2-Chloromandelic acid (CAS 52950-19-3)
- Methyl 3-Chloro-5-hydroxybenzoate (CAS 98406-04-3)
- Zidovudine impurity B (CAS 61008-98-8)
- Saxagliptin Impurity 40 (CAS 361442-00-4)
- Bromazepam EP Impurity B (CAS 41526-21-0)
- Empagliflozin Impurity 172 (CAS CATO-C4X-1065172)
- 6-Bromo-3-chloro-1H-pyrazolo[4,3-b]pyridine (CAS 1391123-68-4)
- 5-Acetamido-1-methyl-1h-pyrazole-3-carboxylic acid (CAS 1174306-96-7)
- Udenafil Impurity N45 (CAS 936951-20-1)
- 2-Amino-3-cyanopyridine (CAS 24517-64-4)
- 4-Chloro-6-nitroquinazoline hydrochloride (CAS 220488-24-4)
- Fluazifop-P (free acid) (CAS 83066-88-0)
- (Leu31,Pro3?)-Neuropeptide Y (human, rat) trifluoroacetate salt (CAS 132699-73-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com