Zidovudine impurity B CAS 61008-98-8
| CAS No. | 61008-98-8 |
| Molecular Formula | C8H7ClO3 |
| Molecular Weight | 186.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Zidovudine impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Zidovudine impurity B (CAS 61008-98-8), molecular formula C8H7ClO3 and molecular weight 186.59 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Zidovudine impurity B is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 186.59 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H7ClO3 |
| Molecular Weight | 186.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
Related Zidovudine Standards
- Zidovudine Impurity N6 (CAS 32189-36-9)
- Zidovudine Impurity F (CAS 16053-52-4)
- Zidovudine Impurity 19 (CAS CATO-C4X-178319)
- Zidovudine EP Impurity C (CAS 65-71-4)
- Zidovudine EP Impurity D (CAS 76-84-6)
- Zidovudine EP Impurity B (CAS 25526-94-7)
- Zidovudine Impurity 04 (CAS 73971-82-1)
- Zidovudine Impurity 13 (CAS 123606-70-2)
Recommended Standards
- (S)-2-Chloromandelic acid (CAS 52950-19-3)
- Methyl 5-chloro-2-hydroxybenzoate (CAS 4068-78-4)
- Noradrenaline EP Impurity E (CAS 54234-59-2)
- 4-Chloromandelic acid (CAS 492-86-4)
- (2,6-Bis((dimethylamino)methyl)phenyl)(bromo)platinum (CAS 67507-09-9)
- Ethyl 4-(chlorosulfonyl)butanoate (CAS 319452-60-3)
- 2-(4-Acetamido-3-methoxybenzenesulfonamido)-3-(1h-indol-3-yl)propanoic acid (CAS 1396966-98-5)
- 4-{4-[(4-chlorophenyl)sulfanyl]-2-phenylpyrimidine-5-carbonyl}morpholine (CAS 477854-71-0)
- (5-Bromo-2-chloropyridin-4-yl)(morpholino)methanone (CAS 1870258-51-7)
- 1-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrazol-1-yl)-2,2,2-trifluoroethan-1-one (CAS 306976-65-8)
- 4-Amino-6-methylpyrimidine-2,5-diol (CAS 87834-03-5)
- Clinofibrate (CAS 30299-08-2)
- Varenicline Impurity 32 (CAS 26326-70-5)
- Semaglutide impurity 107 (CAS CATO-C4X-2226107)
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