Atracurium Impurity 54 (R-Tetrahydropapaverine) HCl CAS 54417-53-7

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.54417-53-7
Molecular FormulaC20H25NO4
Molecular WeightN/A
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Atracurium Impurity 54 (R-Tetrahydropapaverine) HCl CAS 54417-53-7 chemical structure

Description

CATO supplies Atracurium Impurity 54 (R-Tetrahydropapaverine) HCl (CAS 54417-53-7), a pharmacopoeial impurity reference standard (molecular formula C20H25NO4HCl, MW 379.88 g/mol) used for the identification and quantification of trace impurities in APIs.

Structurally, Atracurium Impurity 54 (R-Tetrahydropapaverine) HCl (C20H25NO4HCl) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 379.88 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Atracurium Impurity 54 (R-Tetrahydropapaverine) HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC20H25NO4 HCl
Molecular Weight379.88 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1972
Halogen ContentCl-containing
Nitrogen Atoms1

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