Rivaroxaban Impurity N6 CAS 5466-93-3
| CAS No. | 5466-93-3 |
| Molecular Formula | C12H16N2O4 |
| Molecular Weight | 252.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Rivaroxaban Impurity N6 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Rivaroxaban Impurity N6 (CAS 5466-93-3), a pharmacopoeial impurity reference standard (molecular formula C12H16N2O4, MW 252.27 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Rivaroxaban Impurity N6 (C12H16N2O4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C12H16N2O4 |
| Molecular Weight | 252.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
Related Rivaroxaban Standards
- Rivaroxaban Impurity 157 (CAS 1252018-07-7)
- Rivaroxaban Impurity 120 (CAS CATO-C4X-1090120)
- Rivaroxaban Impurity 85 (CAS 1218777-30-0)
- Rivaroxaban Impurity 199 (CAS CATO-C4X-1090199)
- Rivaroxaban Impurity 118 (CAS CATO-C4X-1090118)
- Rivaroxaban Impurity 212 (CAS CATO-C4X-1090212)
- Rivaroxaban Impurity 71 (CAS 811450-82-5)
- Rivaroxaban Impurity 143 (CAS CATO-C4X-1090143)
Recommended Standards
- Quinolin-8-ylmethyl 1H-pyrrole-3-carboxylate (CAS 649727-13-9)
- Tert-butyl (2-methyl-5-nitrophenyl)carbamate (CAS 329763-31-7)
- Quinolin-5-ylmethyl 1H-pyrrole-3-carboxylate (CAS 649727-10-6)
- tert-Butyl (2-methyl-6-nitrophenyl)carbamate (CAS 885953-51-5)
- Finerenone Impurity 81 (CAS CATO-C4X-288081)
- Cyproheptadine Impurity 10 (CAS 92496-64-5)
- Tulobuterol Impurity 12 (CAS 14185-28-5)
- Tert-butyl 5-propionyl-1H-pyrrolo[3,2-b]pyridine-1-carboxylate (CAS 1407180-80-6)
- Ytterbium(III) 2,2,2-trifluoroacetate (CAS 87863-62-5)
- 2-(Aminomethyl)cyclopentanone Hydrochloride (CAS 1360547-45-0)
- benzyl imidothiocarbamate hydrochloride,HCl (CAS 621-85-2)
- 6-(3-Chloro-4-fluorophenoxy)hexanenitrile (CAS 1443342-23-1)
- 4,5-Dibromophthalonitrile (CAS 86938-64-9)
- Amyloid Precursor Frameshift Mutant C-Terminal Peptide trifluoroacetate salt (CAS 189125-14-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com