Etoricoxib Impurity 36 CAS 874-87-3

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.874-87-3
Molecular FormulaC8H9ClS
Molecular Weight172.68 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Etoricoxib Impurity 36 CAS 874-87-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 172.68 g/mol gives Etoricoxib Impurity 36 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Etoricoxib Impurity 36 (CAS 874-87-3) is a certified pharmaceutical impurity reference standard with the molecular formula C8H9ClS and a molecular weight of 172.68 g/mol.

The molecular framework of Etoricoxib Impurity 36 (C8H9ClS) is characterized by sulfur-containing functionality, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Etoricoxib Impurity 36 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H9ClS
Molecular Weight172.68 g/mol
Purity97%+
StorageStore at 2-8°C, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentCl-containing
Sulfur Atoms1

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