Amitriptyline Hydrochloride CAS 549-18-8
| CAS No. | 549-18-8 |
| Molecular Formula | C20H23N |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Amitriptyline Hydrochloride (C20H23NHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Amitriptyline Hydrochloride (CAS 549-18-8), a certified reference material (molecular formula C20H23NHCl, MW 313.87 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Amitriptyline Hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H23N HCl |
| Molecular Weight | 313.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Amitriptyline Standards
- Amitriptyline EP Impurity D (CAS 1159-03-1)
- Amitriptyline EP Impurity F (CAS 1159-82-6)
- Amitriptyline EP Impurity A (CAS 1210-35-1)
- Amitriptyline Hydrochloride - Impurity F (Oxalate Salt) (CAS 1246833-15-7)
- Amitriptyline-13C3 Hydrochloride (CAS 1329837-86-6)
- Amitriptyline-d6 Hydrochloride (CAS 203645-63-0)
- Amitriptyline EP Impurity C-d3 HCl (CAS 203784-52-5)
- Amitriptyline EP Impurity E HCl (Mixture of Diastereomers) (CAS 26360-49-6(free base))
Recommended Standards
- (S)-1-(tert-butoxycarbonyl)-3,3-difluoropiperidine-2-carboxylic acid (CAS 2165735-31-7)
- 3,6-Dichloro-5-(difluoromethyl)pyridin-2-ol (CAS 1805332-69-7)
- 6-Fluoro-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one (CAS 642491-84-7)
- 4-Bromo-N-(3,4-dichlorophenyl)benzamide (CAS 56661-53-1)
- (6-Chloro-4-methylpyridin-2-yl)methanol (CAS 1227601-23-1)
- Celecoxib Impurity 42 (CAS CATO-C4X-104342)
- 2-Chloro-1-(pyrrolidin-2-yl)ethan-1-one (CAS 1314972-60-5)
- 2-Methyl-1-(1,1,2,2-tetrafluoroethoxy)propane (CAS 18180-34-2)
- 2-(5-Bromopyrimidin-2-yl)propan-1-amine (CAS 1340559-70-7)
- 3X Flag Peptide trifluoroacetate salt (CAS 402750-12-3)
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