Carteolol EP Impurity G CAS 54945-72-1
| CAS No. | 54945-72-1 |
| Molecular Formula | C12H15NO4 |
| Molecular Weight | 237.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Carteolol EP Impurity G is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Carteolol EP Impurity G (CAS 54945-72-1, C12H15NO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Carteolol EP Impurity G (C12H15NO4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Carteolol EP Impurity G meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H15NO4 |
| Molecular Weight | 237.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Nitrogen Atoms | 1 |
Related Carteolol Standards
- Carteolol Impurity 22 (CAS CATO-C4X-228722)
- Carteolol Impurity 20 (CAS CATO-C4X-228720)
- Carteolol Impurity 19 (CAS CATO-C4X-228719)
- Carteolol Impurity 31 (CAS CATO-C4X-228731)
- Carteolol EP Impurity F (CAS 2748462-60-2)
- Carteolol EP Impurity C (CAS 51781-14-7)
- Carteolol EP Impurity D (CAS 51781-13-6)
- Carteolol Impurity 33 (CAS 34685-03-5)
Recommended Standards
- Bromfenac Impurity 23 (CAS 51135-38-7)
- Indobufen Impurity 58 (CAS 91642-00-1)
- Noscapine impurity 3 (CAS 82-54-2)
- Piroxicam Impurity 26 (CAS 1942748-12-1)
- Sildenafil Impurity 30 (CAS 139755-95-6)
- Roxithromycin impurity 30 (CAS CATO-C4X-130330)
- Vonoprazan Impurity 304 (CAS 57331-00-7)
- Semaglutide Impurity 191 (CAS CATO-C4X-2226191)
- Zn(II)Phthalocyaninetetrasulfonicacid (CAS 61586-86-5)
- 5-(2-Chlorophenyl)-4-ethyl-4H-1,2,4-triazole-3-thiol (CAS 26029-13-0)
- 2,2-Dimethyl-N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)butanamide (CAS 2246671-57-6)
- N-Fmoc-4-(tert-butoxycarbonylmethoxy)-L-phenylalanine (CAS 181951-92-8)
- 4-Chloro-2-((2-chloro-5-(trifluoromethyl)phenyl)sulfonamido)benzoic acid (CAS 749896-99-9)
- Peptide Impurity 64 (CAS CATO-CPTD788964)
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